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Anti-CAMKIV Antibody (5K734)

(Synonyms: D18Bwg0362e, CaMKIV/Gr, CaMKIV, calcium/calmodulin-dependent protein kinase IV, AI666733, A430110E23Rik) Copy Product Info
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Synonyms: D18Bwg0362e, CaMKIV/Gr, CaMKIV, calcium/calmodulin-dependent protein kinase IV, AI666733, A430110E23Rik

Catalog No. TMAC-00550 Copy Product Info
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Anti-CAMKIV Antibody (5K734) is a Rabbit antibody targeting CAMKIV. Anti-CAMKIV Antibody (5K734) can be used in FCM,ICC,IF,IHC,WB.
Anti-CAMKIV Antibody
(5K734)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2987-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CAMKIV Antibody (5K734) is a Rabbit antibody targeting CAMKIV. Anti-CAMKIV Antibody (5K734) can be used in FCM,ICC,IF,IHC,WB.
SynonymsD18Bwg0362e, CaMKIV/Gr, CaMKIV, calcium/calmodulin-dependent protein kinase IV, AI666733, A430110E23Rik
Ig Type
IgG
Clone
5K734
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is a ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes designated α, β, γ and δ, which may or may not be co-expressed in the same tissue type. CaMKIV is stimulated by Ca2+ and CaM but also requires phosphorylation by a CaMK for full activation. Stimulation of the T cell receptor CD3 signaling complex with an CD3 monoclonal antibody leads to a 10-40 fold increase in CaMKIV activity. An additional kinase, CaMKK, functions to activate CaMKI through the specific phosphorylation of the regulatory Threonine residue at position 177.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: C-terminus human CAMKIV
Antigen Species
Human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 52 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Related Tags: Anti-CAMKIV Antibody (5K734) molecular weight