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Anti-TINF2 Antibody (2F670) is an antibody targeting TINF2. Anti-TINF2 Antibody (2F670) can be used in ELISA, WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $207 | 7-10 days | |
100 μL | $347 | 7-10 days |
Description | Antibody Type: Recombinant Rabbit Monoclonal Application: ELISA, WB Reactivity: Human, Mouse, Rat |
Alias | TRF1-interacting nuclear protein 2, TINF 2, TIN2, TERF1-interacting nuclear factor 2 |
Ig Type | Rabbit IgG |
Clone | 2F670 |
Reactivity | Human, Mouse, Rat |
Verified Activity | Western Blot -Positive WB detected in: RAW264.7 whole cell lysate, HL-60 whole cell lysate, Mouse Herat whole cell lysate, Mouse Brain whole cell lysate -All lanes: Tin2 antibody at 1:1000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 51, 40, 16 kDa -Observed band size: 51 kDa |
Application | ELISA, WB |
Recommended Dose | WB:1:500-1:5000. |
Antibody Type | Monoclonal |
Subcellular Localization | Nucleus. Chromosome, telomere. Note=Associated with telomeres.; [Isoform 1]: Nucleus matrix. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Research Background | Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix. |
Conjucates | Unconjugated |
Immunogen | A synthetic peptide: Human Tin2 |
Antigen Species | Human |
Gene ID | 26277 |
Uniprot ID | |
Biology Area | Epigenetics and Nuclear Signaling |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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