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Anti-TINF2 Antibody (2F670) is an antibody targeting TINF2. Anti-TINF2 Antibody (2F670) can be used in ELISA,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $207 | 7-10 days | 7-10 days | |
| 100 μL | $347 | 7-10 days | 7-10 days |
| Description | Anti-TINF2 Antibody (2F670) is an antibody targeting TINF2. Anti-TINF2 Antibody (2F670) can be used in ELISA,WB. |
| Synonyms | TRF1-interacting nuclear protein 2, TINF 2, TIN2, TERF1-interacting nuclear factor 2 |
| Ig Type | Rabbit IgG |
| Clone | 2F670 |
| Reactivity | Human, Mouse, Rat |
| Verified Activity | Western Blot -Positive WB detected in: RAW264.7 whole cell lysate, HL-60 whole cell lysate, Mouse Herat whole cell lysate, Mouse Brain whole cell lysate -All lanes: Tin2 antibody at 1:1000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 51, 40, 16 kDa -Observed band size: 51 kDa |
| Application | |
| Recommended Dose | WB:1:500-1:5000. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Nucleus. Chromosome, telomere. Note=Associated with telomeres.; [Isoform 1]: Nucleus matrix. |
| Tissue Specificity | Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human Tin2 |
| Antigen Species | Human |
| Gene Name | TINF2 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Epigenetics and Nuclear Signaling |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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