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Anti-NR4A1 Antibody (7O127)
(Synonyms: Testicular receptor 3, ST-59, Orphan nuclear receptor TR3, Orphan nuclear receptor HMR, Nuclear receptor subfamily 4immunitygroup A member 1, Nuclear hormone receptor NUR/77 (Nur77), NR4A1, NAK1, HMR, GFRP1, Early response protein NAK1) Copy Product Info
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Synonyms: Testicular receptor 3, ST-59, Orphan nuclear receptor TR3, Orphan nuclear receptor HMR, Nuclear receptor subfamily 4immunitygroup A member 1, Nuclear hormone receptor NUR/77 (Nur77), NR4A1, NAK1, HMR, GFRP1, Early response protein NAK1
Catalog No. TMAC-02908 Copy Product Info
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Anti-NR4A1 Antibody (7O127) is a Rabbit antibody targeting NR4A1. Anti-NR4A1 Antibody (7O127) can be used in ICC/IF,IHC,WB.
Anti-NR4A1 Antibody
(7O127)
(7O127)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $296 | 7-10 days | 7-10 days | |
| 100 μL | $498 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-NR4A1 Antibody (7O127) is a Rabbit antibody targeting NR4A1. Anti-NR4A1 Antibody (7O127) can be used in ICC/IF,IHC,WB. |
| Synonyms | Testicular receptor 3, ST-59, Orphan nuclear receptor TR3, Orphan nuclear receptor HMR, Nuclear receptor subfamily 4immunitygroup A member 1, Nuclear hormone receptor NUR/77 (Nur77), NR4A1, NAK1, HMR, GFRP1, Early response protein NAK1 |
| Ig Type | IgG |
| Clone | 7O127 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC: 1:50-200; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Nurr1 (Nur-related factor 1) and Nur77 (also designated NGFI-B) encode orphan nuclear receptors which may comprise an additional subfamily within the nuclear receptor superfamily. The rat and human homologs of mouse Nurr1 are designated RNR1 and NOT, respectively. Both Nurr1 and Nur77 are growth factor inducible immediate early response genes. Induction of both Nurr1 and Nur77 is seen after membrane depolarization while only Nur77 induction is seen with NGF stimulation. JunD acts as a mediator for Nur77. An increase in Nur77 expression is seen in activated T cells during G0 to G1 transition and throughout the G1 phase. In addition to its function as an immediate early gene, Nur77 may play a role in TCR-mediated apoptosis. Cyclosporin A, a potent immunosuppressant, has been shown to inhibit the ability of Nur77 to bind DNA. A dominant negative form of Nur77 can protect T cell hybridomas from activation-induced apoptosis. However, the absolute requirement of Nur77 for TCR-mediated apoptosis is still under debate. |
| Conjucates | Unconjugated |
| Immunogen | Synthetic peptide within Human NUR77 aa 10-49 / 598 |
| Antigen Species | Human |
| Uniprot ID |
| Molecular Weight | Theoretical: 64 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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