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Anti-EIF2AK2 Antibody (3D60)

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Catalog No. TMAC-03357

Anti-EIF2AK2 Antibody (3D60) is a Rabbit antibody targeting EIF2AK2. Anti-EIF2AK2 Antibody (3D60) can be used in WB,ICC/IF,IHC,IP.

Anti-EIF2AK2 Antibody (3D60)

Anti-EIF2AK2 Antibody (3D60)

😃Good
Catalog No. TMAC-03357
Anti-EIF2AK2 Antibody (3D60) is a Rabbit antibody targeting EIF2AK2. Anti-EIF2AK2 Antibody (3D60) can be used in WB,ICC/IF,IHC,IP.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4967-10 days
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Product Introduction

Bioactivity
Description
Anti-EIF2AK2 Antibody (3D60) is a Rabbit antibody targeting EIF2AK2. Anti-EIF2AK2 Antibody (3D60) can be used in WB,ICC/IF,IHC,IP.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:1000-5000; IHC: 1:50-100; ICC/IF: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundAn interferon-inducible, RNA-dependent protein serine/threonine kinase (PKR) has been described. PKR in earlier literature is variously known as DAI, dsJ, PI kinase, p65, p67 or TIK for the mouse kinase; and p68 or p69 for the human kinase. The PKR kinase substrate is the a subunit of protein synthesis initiation factor eIF-2. Phosphorylation of eIF-2a on serine-51 results in inhibition of translation. Molecular cDNA clones have been isolated from both human and mouse cells. The serine/threonine kinase catalytic domains map to the carboxy terminal half of the protein while the RNA-binding domains are located in the amino terminal region. Three kinds of regulation of PKR enzymatic activity have been described. These include transcriptional regulation in response to interferon, an autoregulatory mechanism controlling PKR expression at the level of translation and post-translational regulation by RNA mediated autophosphorylation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 68 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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