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Anti-MRE11 Antibody (6B152)

(Synonyms: OTTHUMP00000236833, OTTHUMP00000236832, OTTHUMP00000236831, OTTHUMP00000236830, MRE11b, MRE11A, MRE11_HUMAN, MRE11 meiotic recombination 11 homolog A (S. cerevisiae), MRE11 meiotic recombination 11 homolog A, MRE11 homolog A, MRE11 homolog 1, MRE 11b, MRE 11a, Mre 11, MmMRE11A, meiotic recombination 11 homolog A (S. cerevisiae), Meiotic recombination 11 homolog A, Meiotic recombination 11 homolog 1, meiotic recombination (S. cerevisiae) 11 homolog A, HNGS1, endo/exonuclease Mre11, Double-strand break repair protein MRE11A, Double strand break repair protein MRE11A, DNA recombination and repair protein, ATLD, Ataxia telangiectasia disorder like, AT like disease) Copy Product Info
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Synonyms: OTTHUMP00000236833, OTTHUMP00000236832, OTTHUMP00000236831, OTTHUMP00000236830, MRE11b, MRE11A, MRE11_HUMAN, MRE11 meiotic recombination 11 homolog A (S. cerevisiae), MRE11 meiotic recombination 11 homolog A, MRE11 homolog A, MRE11 homolog 1, MRE 11b, MRE 11a, Mre 11, MmMRE11A, meiotic recombination 11 homolog A (S. cerevisiae), Meiotic recombination 11 homolog A, Meiotic recombination 11 homolog 1, meiotic recombination (S. cerevisiae) 11 homolog A, HNGS1, endo/exonuclease Mre11, Double-strand break repair protein MRE11A, Double strand break repair protein MRE11A, DNA recombination and repair protein, ATLD, Ataxia telangiectasia disorder like, AT like disease

Catalog No. TMAC-02645 Copy Product Info
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Anti-MRE11 Antibody (6B152) is a Rabbit antibody targeting MRE11. Anti-MRE11 Antibody (6B152) can be used in IHC,WB.
Anti-MRE11 Antibody
(6B152)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-MRE11 Antibody (6B152) is a Rabbit antibody targeting MRE11. Anti-MRE11 Antibody (6B152) can be used in IHC,WB.
SynonymsOTTHUMP00000236833, OTTHUMP00000236832, OTTHUMP00000236831, OTTHUMP00000236830, MRE11b, MRE11A, MRE11_HUMAN, MRE11 meiotic recombination 11 homolog A (S. cerevisiae), MRE11 meiotic recombination 11 homolog A, MRE11 homolog A, MRE11 homolog 1, MRE 11b, MRE 11a, Mre 11, MmMRE11A, meiotic recombination 11 homolog A (S. cerevisiae), Meiotic recombination 11 homolog A, Meiotic recombination 11 homolog 1, meiotic recombination (S. cerevisiae) 11 homolog A, HNGS1, endo/exonuclease Mre11, Double-strand break repair protein MRE11A, Double strand break repair protein MRE11A, DNA recombination and repair protein, ATLD, Ataxia telangiectasia disorder like, AT like disease
Ig Type
IgG
Clone
6B152
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundComponent of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11. RAD50 may be required to bind DNA ends and hold them in close proximity. This could facilitate searches for short or long regions of sequence homology in the recombining DNA templates, and may also stimulate the activity of DNA ligases and/or restrict the nuclease activity of MRE11 to prevent nucleolytic degradation past a given point. The complex may also be required for DNA damage signaling via activation of the ATM kinase. In telomeres the MRN complex may modulate t-loop formation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 81 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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