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Anti-MRE11 Antibody (6B152)
😃Good
Catalog No. TMAC-02645
Alias OTTHUMP00000236833, OTTHUMP00000236832, OTTHUMP00000236831, OTTHUMP00000236830, MRE11b, MRE11A, MRE11_HUMAN, MRE11 meiotic recombination 11 homolog A (S. cerevisiae), MRE11 meiotic recombination 11 homolog A, MRE11 homolog A, MRE11 homolog 1, MRE 11b, MRE 11a, Mre 11, MmMRE11A, meiotic recombination 11 homolog A (S. cerevisiae), Meiotic recombination 11 homolog A, Meiotic recombination 11 homolog 1, meiotic recombination (S. cerevisiae) 11 homolog A, HNGS1, endo/exonuclease Mre11, Double-strand break repair protein MRE11A, Double strand break repair protein MRE11A, DNA recombination and repair protein, ATLD, Ataxia telangiectasia disorder like, AT like disease
Anti-MRE11 Antibody (6B152) is a Rabbit antibody targeting MRE11. Anti-MRE11 Antibody (6B152) can be used in IHC,WB.
Anti-MRE11 Antibody (6B152)
Anti-MRE11 Antibody (6B152)
😃Good
Catalog No. TMAC-02645Alias OTTHUMP00000236833, OTTHUMP00000236832, OTTHUMP00000236831, OTTHUMP00000236830, MRE11b, MRE11A, MRE11_HUMAN, MRE11 meiotic recombination 11 homolog A (S. cerevisiae), MRE11 meiotic recombination 11 homolog A, MRE11 homolog A, MRE11 homolog 1, MRE 11b, MRE 11a, Mre 11, MmMRE11A, meiotic recombination 11 homolog A (S. cerevisiae), Meiotic recombination 11 homolog A, Meiotic recombination 11 homolog 1, meiotic recombination (S. cerevisiae) 11 homolog A, HNGS1, endo/exonuclease Mre11, Double-strand break repair protein MRE11A, Double strand break repair protein MRE11A, DNA recombination and repair protein, ATLD, Ataxia telangiectasia disorder like, AT like disease
Anti-MRE11 Antibody (6B152) is a Rabbit antibody targeting MRE11. Anti-MRE11 Antibody (6B152) can be used in IHC,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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| Description | Anti-MRE11 Antibody (6B152) is a Rabbit antibody targeting MRE11. Anti-MRE11 Antibody (6B152) can be used in IHC,WB. |
| Synonyms | OTTHUMP00000236833, OTTHUMP00000236832, OTTHUMP00000236831, OTTHUMP00000236830, MRE11b, MRE11A, MRE11_HUMAN, MRE11 meiotic recombination 11 homolog A (S. cerevisiae), MRE11 meiotic recombination 11 homolog A, MRE11 homolog A, MRE11 homolog 1, MRE 11b, MRE 11a, Mre 11, MmMRE11A, meiotic recombination 11 homolog A (S. cerevisiae), Meiotic recombination 11 homolog A, Meiotic recombination 11 homolog 1, meiotic recombination (S. cerevisiae) 11 homolog A, HNGS1, endo/exonuclease Mre11, Double-strand break repair protein MRE11A, Double strand break repair protein MRE11A, DNA recombination and repair protein, ATLD, Ataxia telangiectasia disorder like, AT like disease |
| Ig Type | IgG |
| Clone | 6B152 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of Mre11 on different cells lysates using anti-Mre11 antibody at 1/500 dilution. Positive control: Line 1: 293T, Line 2: Hela. 2. Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti- Mre11 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue using anti- Mre11 antibody. Counter stained with hematoxylin. |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11. RAD50 may be required to bind DNA ends and hold them in close proximity. This could facilitate searches for short or long regions of sequence homology in the recombining DNA templates, and may also stimulate the activity of DNA ligases and/or restrict the nuclease activity of MRE11 to prevent nucleolytic degradation past a given point. The complex may also be required for DNA damage signaling via activation of the ATM kinase. In telomeres the MRN complex may modulate t-loop formation. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 81 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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