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Anti-WNK1 Antibody (1S306)

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Catalog No. TMAC-04286

Anti-WNK1 Antibody (1S306) is a Rabbit antibody targeting WNK1. Anti-WNK1 Antibody (1S306) can be used in WB,IHC.

Anti-WNK1 Antibody (1S306)

Anti-WNK1 Antibody (1S306)

😃Good
Catalog No. TMAC-04286
Anti-WNK1 Antibody (1S306) is a Rabbit antibody targeting WNK1. Anti-WNK1 Antibody (1S306) can be used in WB,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4987-10 days
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Product Introduction

Bioactivity
Description
Anti-WNK1 Antibody (1S306) is a Rabbit antibody targeting WNK1. Anti-WNK1 Antibody (1S306) can be used in WB,IHC.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundSerine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D and SGK1. Controls sodium and chloride ion transport by inhibiting the activity of WNK4, by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide-sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganization. Phosphorylates NEDD4L. Acts as a scaffold to inhibit SLC4A4, SLC26A6 as well as CFTR activities and surface expression, recruits STK39 which mediates the inhibition.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthesized peptide: within Human WNK1 aa 100-200 (Cysteine residue)
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 250/300 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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