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Anti-LGR-5 Antibody (8V603)
(Synonyms: LGR5, HG38, G-protein coupled receptor HG38, G-protein coupled receptor 67, G-protein coupled receptor 49, GPR67, GPR49) Copy Product Info
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Synonyms: LGR5, HG38, G-protein coupled receptor HG38, G-protein coupled receptor 67, G-protein coupled receptor 49, GPR67, GPR49
Catalog No. TMAH-00695 Copy Product Info
🥰Excellent
Anti-LGR-5 Antibody (8V603) is an antibody targeting LGR-5. Anti-LGR-5 Antibody (8V603) can be used in ELISA,FCM,WB.
Anti-LGR-5 Antibody
(8V603)
(8V603)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $347 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-LGR-5 Antibody (8V603) is an antibody targeting LGR-5. Anti-LGR-5 Antibody (8V603) can be used in ELISA,FCM,WB. |
| Synonyms | LGR5, HG38, G-protein coupled receptor HG38, G-protein coupled receptor 67, G-protein coupled receptor 49, GPR67, GPR49 |
| Ig Type | Rabbit IgG |
| Clone | 8V603 |
| Reactivity | Human, Rat |
| Application | |
| Recommended Dose | WB:1:500-1:5000; FCM:1:20-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. |
| Tissue Specificity | Expressed in skeletal muscle, placenta, spinal cord, and various region of brain. Expressed at the base of crypts in colonic and small mucosa stem cells. In premalignant cancer expression is not restricted to the cript base. Overexpressed in cancers of th |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human LGR5/GPR49 |
| Antigen Species | Human |
| Gene Name | LGR5 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cancer, Signal transduction, Stem cells |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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