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Anti-FOS Antibody (8B580) is a Rabbit antibody targeting FOS. Anti-FOS Antibody (8B580) can be used in FCM,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $496 | 7-10 days |
| Description | Anti-FOS Antibody (8B580) is a Rabbit antibody targeting FOS. Anti-FOS Antibody (8B580) can be used in FCM,WB. |
| Synonyms | Proto-oncogene c-Fos, p55, Oncogene FOS, G0S7, G0/G1 switch regulatory protein 7, FBJ Osteosarcoma Virus, FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS), Cellular oncogene c fos, C FOS, AP 1, Activator protein 1 |
| Ig Type | IgG |
| Clone | 8B580 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Flow cytometric analysis of NIH/3T3 cells with c-Fos antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. ![]() |
| Application | |
| Recommended Dose | WB: 1:1000; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The c-Fos oncogene was initially detected in two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phospho-protein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA response elements, c-Fos proteins are only active as heterodimers with members of the Jun gene family. Functional homologs of c-Fos include the Fra-1, Fra-2 and Fos B genes. In addition, selected ATF/CREB family members can form leucine zipper dimers with Fos and Jun. Different dimers exhibit differential specificity and affinity for AP-1 and CRE sites. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 62 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |

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