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Anti-TACC3 Antibody (7N742) (Synonyms: Transforming acidic coiled-coil-containing protein 3, TACC 3, ERIC-1, ...)

Catalog No. TMAC-03952 Copy Product Info
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Anti-TACC3 Antibody (7N742) is a Rabbit antibody targeting TACC3. Anti-TACC3 Antibody (7N742) can be used in ICC/IF,IHC,WB.

Anti-TACC3 Antibody (7N742)

Copy Product Info
🥰Excellent
Catalog No. TMAC-03952
Synonyms Transforming acidic coiled-coil-containing protein 3, TACC 3, ERIC-1, ERIC1

Anti-TACC3 Antibody (7N742) is a Rabbit antibody targeting TACC3. Anti-TACC3 Antibody (7N742) can be used in ICC/IF,IHC,WB.

Anti-TACC3 Antibody
(7N742)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-TACC3 Antibody (7N742) is a Rabbit antibody targeting TACC3. Anti-TACC3 Antibody (7N742) can be used in ICC/IF,IHC,WB.
SynonymsTransforming acidic coiled-coil-containing protein 3, TACC 3, ERIC-1, ERIC1
Ig Type
IgG
Clone
7N742
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of TACC3 on different lysates using anti-TACC3 antibody at 1/1,000 dilution. Positive control: Lane 1: HT29, Lane 2: Hela.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-TACC3 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-TACC3 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-TACC3 antibody. Counter stained with hematoxylin.
5. ICC staining TACC3 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. ICC staining TACC3 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
verifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundTACC1 (transforming acidic coiled coil gene 1) is one of three TACC family members, which are thought to be involved in breast tumorigenesis. TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 8, 10, and 4. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 140 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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