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Anti-Mib1 Antibody (6F547)

😃Good
Catalog No. TMAC-02582

Anti-Mib1 Antibody (6F547) is a Rabbit antibody targeting Mib1. Anti-Mib1 Antibody (6F547) can be used in WB,ICC,IHC.

Anti-Mib1 Antibody (6F547)

Anti-Mib1 Antibody (6F547)

😃Good
Catalog No. TMAC-02582
Anti-Mib1 Antibody (6F547) is a Rabbit antibody targeting Mib1. Anti-Mib1 Antibody (6F547) can be used in WB,ICC,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4967-10 days
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Product Introduction

Bioactivity
Description
Anti-Mib1 Antibody (6F547) is a Rabbit antibody targeting Mib1. Anti-Mib1 Antibody (6F547) can be used in WB,ICC,IHC.
Ig Type
IgG
Reactivity
Human,Mouse
Application
Recommended Dose
IHC: 1:50-200; ICC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundE3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing apoptotic effects of DAPK1 to promote TNF-induced apoptosis (By similarity). Involved in ubiquitination of centriolar satellite CEP131, CEP290 and PCM1 proteins and hence inhibits primary cilium formation in proliferating cells. Mediates 'Lys-63'-linked polyubiquitination of TBK1, which probably participates in kinase activation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: within N-terminal human Mib1
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 110 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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