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Synonyms: SH2/SH3 Adapter GRB2, Protein Ash, Growth Factor Receptor-Bound Protein 2, GRB2, ASH, Adapter Protein GRB2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $349 | 7-10 days | 7-10 days |
| Description | Anti-GRB2 Antibody (9L258) is an antibody targeting GRB2. Anti-GRB2 Antibody (9L258) can be used in ELISA,IHC,WB. |
| Synonyms | SH2/SH3 Adapter GRB2, Protein Ash, Growth Factor Receptor-Bound Protein 2, GRB2, ASH, Adapter Protein GRB2 |
| Ig Type | Rabbit IgG |
| Clone | 9L258 |
| Reactivity | Human, Mouse, Rat |
| Application | |
| Recommended Dose | WB:1:500-1:5000; IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Nucleus. Cytoplasm. Endosome. Golgi apparatus. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human GRB2 |
| Antigen Species | Human |
| Gene Name | GRB2 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cancer, Signal transduction |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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