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Anti-HRH3 Antibody (8E966) is an antibody targeting HRH3. Anti-HRH3 Antibody (8E966) can be used in ELISA, FC.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $208 | 7-10 days | |
100 μL | $348 | 7-10 days |
Description | Anti-HRH3 Antibody (8E966) is an antibody targeting HRH3. Anti-HRH3 Antibody (8E966) can be used in ELISA, FC. |
Alias | HRH 3, Histamine H3 receptor, HH3R, H3R, G-protein coupled receptor 97, GPCR97 |
Ig Type | Rabbit IgG |
Clone | 8E966 |
Reactivity | Human |
Verified Activity | Overlay Peak curve showing SH-SY5Y cells surface stained with TMAH-00566 (red line) at 1:50. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1µg/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4°C.Control antibody (green line) was rabbit IgG (1µg/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed. |
Application | ELISA, FC |
Recommended Dose | FC:1:50-1:200. |
Antibody Type | Monoclonal |
Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Research Background | The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 neither modified adenylate cyclase activity nor induced intracellular calcium mobilization. |
Conjucates | Unconjugated |
Immunogen | A synthetic peptide: Human HRH3 |
Antigen Species | Human |
Gene ID | 11255 |
Uniprot ID | |
Biology Area | Neuroscience |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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