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Anti-FBXL10 Antibody (6J798)
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Catalog No. TMAC-01451
Alias Protein-containing CXXC domain 2, Protein JEMMA, Protein containing CXXC domain 2, PCCX2, Lysine-specific demethylase 2B, Lysine (K) specific demethylase 2B, KDM2B_HUMAN, kdm2b, Jumonji domain-containing EMSY-interactor methyltransferase motif protein, Jumonji C domain containing histone demethylase 1B, JmjC domain-containing histone demethylation protein 1B, JHDM1B, JEMMA (Jumonji domain EMSY interactor methyltransferase motif) protein, FBXL10, FBXL 10, F-box/LRR-repeat protein 10, F-box protein FBL10, F-box and leucine-rich repeat protein 10, Fbl10, F box protein FBL10, F box and leucine rich repeat protein 10, CXXC-type zinc finger protein 2, CXXC2, [Histone-H3]-lysine-36 demethylase 1B
Anti-FBXL10 Antibody (6J798) is a Mouse antibody targeting FBXL10. Anti-FBXL10 Antibody (6J798) can be used in WB,FCM.
Anti-FBXL10 Antibody (6J798)
Anti-FBXL10 Antibody (6J798)
😃Good
Catalog No. TMAC-01451Alias Protein-containing CXXC domain 2, Protein JEMMA, Protein containing CXXC domain 2, PCCX2, Lysine-specific demethylase 2B, Lysine (K) specific demethylase 2B, KDM2B_HUMAN, kdm2b, Jumonji domain-containing EMSY-interactor methyltransferase motif protein, Jumonji C domain containing histone demethylase 1B, JmjC domain-containing histone demethylation protein 1B, JHDM1B, JEMMA (Jumonji domain EMSY interactor methyltransferase motif) protein, FBXL10, FBXL 10, F-box/LRR-repeat protein 10, F-box protein FBL10, F-box and leucine-rich repeat protein 10, Fbl10, F box protein FBL10, F box and leucine rich repeat protein 10, CXXC-type zinc finger protein 2, CXXC2, [Histone-H3]-lysine-36 demethylase 1B
Anti-FBXL10 Antibody (6J798) is a Mouse antibody targeting FBXL10. Anti-FBXL10 Antibody (6J798) can be used in WB,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $426 | 7-10 days |
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| Description | Anti-FBXL10 Antibody (6J798) is a Mouse antibody targeting FBXL10. Anti-FBXL10 Antibody (6J798) can be used in WB,FCM. |
| Synonyms | Protein-containing CXXC domain 2, Protein JEMMA, Protein containing CXXC domain 2, PCCX2, Lysine-specific demethylase 2B, Lysine (K) specific demethylase 2B, KDM2B_HUMAN, kdm2b, Jumonji domain-containing EMSY-interactor methyltransferase motif protein, Jumonji C domain containing histone demethylase 1B, JmjC domain-containing histone demethylation protein 1B, JHDM1B, JEMMA (Jumonji domain EMSY interactor methyltransferase motif) protein, FBXL10, FBXL 10, F-box/LRR-repeat protein 10, F-box protein FBL10, F-box and leucine-rich repeat protein 10, Fbl10, F box protein FBL10, F box and leucine rich repeat protein 10, CXXC-type zinc finger protein 2, CXXC2, [Histone-H3]-lysine-36 demethylase 1B |
| Clone | 6J798 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of FBXL10 on human FBXL10 recombinant protein using anti-FBXL10 antibody at 1/1,000 dilution. 2. Western blot analysis of FBXL10 on HEK293 (1) and FBXL10-hIgGFc transfected HEK293 (2) cell lysate using anti-FBXL10 antibody at 1/1,000 dilution. 3. Western blot analysis of FBXL10 on A549 cell lysate using anti-FBXL10 antibody at 1/1,000 dilution. 4. Flow cytometric analysis of Hela cells with FBXL10 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red). |
| Application | |
| Recommended Dose | WB: 1:500-1000; FCM: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | FBXL10 (F-box and leucine-rich repeat protein 10), also known as Fbl10, CXXC2 (CXXC-type zinc finger protein 2), PCCX2, KDM2B, JEMMA (jumonji domain, EMSY-interactor, methyltransferase motif protein) or JHDM1B (jumonji C domain-containing histone demethylase 1B), is a nuclear protein that contains one F-box domain, a CXXC-type zinc finger, one JMJC domain, four leucine-rich repeats and one PHD-type zinc finger. FBXL10 belongs to the Fbls class of F-box proteins that contain leucine-rich repeats in addition to their F-box motif. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. In addition to its role in substrate recognition as a component of the E3 complex, FBXL10 functions as a dimethylation-specific demethylase, binding iron as a cofactor and demethylating lysine-36 of Histone H3. This suggests that FBXL10 plays a central role in the histone code. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 152 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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