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Anti-CBX5 Antibody (5G758) (Synonyms: HP1A, Heterochromatin protein 1 homolog alpha (HP1 alpha), Chromobox pro...)

Catalog No. TMAC-02002 Copy Product Info
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Anti-CBX5 Antibody (5G758) is a Rabbit antibody targeting CBX5. Anti-CBX5 Antibody (5G758) can be used in FCM,ICC/IF,IHC,IP,WB.

Anti-CBX5 Antibody (5G758)

Copy Product Info
🥰Excellent
Catalog No. TMAC-02002
Synonyms HP1A, Heterochromatin protein 1 homolog alpha (HP1 alpha), Chromobox protein homolog 5, CBX5, Antigen p25

Anti-CBX5 Antibody (5G758) is a Rabbit antibody targeting CBX5. Anti-CBX5 Antibody (5G758) can be used in FCM,ICC/IF,IHC,IP,WB.

Anti-CBX5 Antibody
(5G758)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CBX5 Antibody (5G758) is a Rabbit antibody targeting CBX5. Anti-CBX5 Antibody (5G758) can be used in FCM,ICC/IF,IHC,IP,WB.
SynonymsHP1A, Heterochromatin protein 1 homolog alpha (HP1 alpha), Chromobox protein homolog 5, CBX5, Antigen p25
Ig Type
IgG
Clone
5G758
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of HP1 alpha on different cell lysates using anti-HP1 alpha antibody at 1/1,000 dilution. Positive control: Lane 1: MCF-7, Lane 2: Hela.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-HP1 alpha antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-HP1 alpha antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-HP1 alpha antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded mouse uterus tissue using anti-HP1 alpha antibody. Counter stained with hematoxylin.
6. ICC staining HP1 alpha in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
7. ICC staining HP1 alpha in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
8. Flow cytometric analysis of SH-SY-5Y cells with HP1 alpha antibody at 1/50 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
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Application
Recommended Dose
WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe family of Heterochromatin Protein 1 (HP1) ("Chromobox Homolog", CBX) are highly conserved adapter proteins, which have important functions in the cell nucleus. These functions include gene repression by heterochromatin formation, transcriptional activation, regulation of binding of cohesion complexes to centromere, sequesteration of genes to nuclear periphery, transcriptional arrest, maintenance of heterochromatin integrity, gene repression at single nucleosome level and gene repression by heterochromatization of euchromatin.Three different paralogs of HP1 are found in mammals, HP1α, HP1βand HP1γ.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 22 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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