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Anti-SLINGSHOT-1L Monoclonal Antibody (4O752)
(Synonyms: SSH1L, SSH1) Copy Product Info
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Synonyms: SSH1L, SSH1
Catalog No. TMAC-03771 Copy Product Info
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Anti-SLINGSHOT-1L Monoclonal Antibody (4O752) is a Mouse antibody targeting SLINGSHOT-1L. Anti-SLINGSHOT-1L Monoclonal Antibody (4O752) can be used in IHC,FCM.
Anti-SLINGSHOT-1L Monoclonal Antibody
(4O752)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 µL | $296 | 7-10 days | 7-10 days | |
| 100 µL | $428 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-SLINGSHOT-1L Monoclonal Antibody (4O752) is a Mouse antibody targeting SLINGSHOT-1L. Anti-SLINGSHOT-1L Monoclonal Antibody (4O752) can be used in IHC,FCM. |
| Synonyms | SSH1L, SSH1 |
| Ig Type | IgG1 |
| Clone | 4O752 |
| Reactivity | Human |
| Verified Activity | 1. Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissue using anti- Slingshot homolog 1 antibody. Counter stained with hematoxylin. 2. Flow cytometric analysis of Hela cells with Slingshot homolog 1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).  , |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Synthesized peptide fragment of human SLINGSHOT-1L (AA: 1032-1044 ) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | SSH1 |
| Gene ID | |
| Protein Name | Protein phosphatase Slingshot homolog 1 |
| Uniprot ID |
| Molecular Weight | Theoretical: 116 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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