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Anti-SLINGSHOT-1L Antibody (4Y112) is a Mouse antibody targeting SLINGSHOT-1L. Anti-SLINGSHOT-1L Antibody (4Y112) can be used in IHC,FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $296 | 7-10 days | |
100 μL | $428 | 7-10 days |
Description | Anti-SLINGSHOT-1L Antibody (4Y112) is a Mouse antibody targeting SLINGSHOT-1L. Anti-SLINGSHOT-1L Antibody (4Y112) can be used in IHC,FCM. |
Synonyms | SSH-like protein 1, SSH-1L, SSH1_HUMAN, Ssh1, SSH 1L, SSH 1, SLINGSHOT1L, Slingshot1, slingshot like 1, slingshot homolog 1, slingshot 1L, Slingshot 1, Protein phosphatase Slingshot homolog 1, OTTMUSP00000031415, mSSH 1L, hSSH-1L, Gm1395, Gm1394, coronin, actin binding protein 1C, Coro1c, AW551225 |
Clone | 4Y112 |
Reactivity | Human |
Verified Activity | 1. Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissue using anti- Slingshot homolog 1 antibody. Counter stained with hematoxylin. 2. Flow cytometric analysis of Hela cells with Slingshot homolog 1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red). |
Application | |
Recommended Dose | IHC: 1:50-200; FCM: 1:50-100 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | Hybridoma Monoclonal Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | Slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein |
Uniprot ID |
Molecular Weight | Theoretical: 116 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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