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Anti-HTR2C Antibody (5H488) (Alias: Serotonin receptor 2C, Serotonin 5-HT-2C receptor, serotonin 2c recepto...)

Catalog No. TMAC-00032 Copy Product Info
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Anti-HTR2C Antibody (5H488) is a Rabbit antibody targeting HTR2C. Anti-HTR2C Antibody (5H488) can be used in IHC,WB.

Anti-HTR2C Antibody (5H488)

Copy Product Info
🥰Excellent
Catalog No. TMAC-00032
Alias Serotonin receptor 2C, Serotonin 5-HT-2C receptor, serotonin 2c receptor, serotonin 1c receptor, HTR2C, Htr1c, 5-hydroxytryptamine(serotonin) receptor 2C, G protein-coupled, 5-hydroxytryptamine receptor 2C, 5-hydroxytryptamine receptor 1C, 5Hydroxytryptamine 2C receptor, 5-HTR2C, 5HTR2C, 5-HT-2C, 5-HT2C, 5HT2C, 5-HT-1C receptor, 5-HT1C, 5 Hydroxytryptamine 2C receptor

Anti-HTR2C Antibody (5H488) is a Rabbit antibody targeting HTR2C. Anti-HTR2C Antibody (5H488) can be used in IHC,WB.

Anti-HTR2C Antibody
(5H488)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4967-10 days7-10 days
In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-HTR2C Antibody (5H488) is a Rabbit antibody targeting HTR2C. Anti-HTR2C Antibody (5H488) can be used in IHC,WB.
SynonymsSerotonin receptor 2C, Serotonin 5-HT-2C receptor, serotonin 2c receptor, serotonin 1c receptor, HTR2C, Htr1c, 5-hydroxytryptamine(serotonin) receptor 2C, G protein-coupled, 5-hydroxytryptamine receptor 2C, 5-hydroxytryptamine receptor 1C, 5Hydroxytryptamine 2C receptor, 5-HTR2C, 5HTR2C, 5-HT-2C, 5-HT2C, 5HT2C, 5-HT-1C receptor, 5-HT1C, 5 Hydroxytryptamine 2C receptor
Ig Type
IgG
Clone
5H488
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of 5HT2C Receptor on A431 (1) AND K562 (2) lysates using anti-5HT2C Receptor antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-5HT2C Receptor antibody. Counter stained with hematoxylin.
verifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundG-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca2+ ions from intracellular stores. Regulates neuronal activity via the activation of short transient receptor potential calcium channels in the brain, and thereby modulates the activation of pro-opiomelacortin neurons and the release of CRH that then regulates the release of corticosterone.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 70 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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