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Anti-RING1 Monoclonal Antibody (3V880)

(Synonyms: RNF1, RING1A) Copy Product Info
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Synonyms: RNF1, RING1A

Catalog No. TMAC-03607 Copy Product Info
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Anti-RING1 Monoclonal Antibody (3V880) is a Mouse antibody targeting RING1. Anti-RING1 Monoclonal Antibody (3V880) can be used in WB,IHC,FCM.

Anti-RING1 Monoclonal Antibody
(3V880)

Pack SizePriceUSA StockGlobal StockQuantity
50 µL$2967-10 days7-10 days
100 µL$4287-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-RING1 Monoclonal Antibody (3V880) is a Mouse antibody targeting RING1. Anti-RING1 Monoclonal Antibody (3V880) can be used in WB,IHC,FCM.
SynonymsRNF1, RING1A
Ig Type
IgG1
Clone
3V880
Reactivity
Human
Verified Activity
1. Western blot analysis of Ring1 on different cell lysate using anti-Ring1 antibody at 1/1,000 dilution. Positive control: Line1: MOLT-4, Line2: LNCaP, Line3: Hela, Line4: HEK-293, Line5: Jurkat.
2. Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue using anti-Ring1 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human rectum cancer tissue using anti-Ring1 antibody. Counter stained with hematoxylin.
4. Flow cytometric analysis of Hela cells with Ring1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
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Application
Recommended Dose
WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/mL
Research BackgroundThis gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human Ring1 (AA: 79-263) expressed in E. Coli.
Antigen Species
Human
Gene Name
RING1
Gene ID
Protein Name
E3 ubiquitin-protein ligase RING1
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 42.4 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Anti-RING1 Monoclonal Antibody (3V880) molecular weight