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Anti-GIT1 Antibody (6A39)

(Synonyms: GRK-interacting protein 1, GRK interacting protein 1, GIT1_HUMAN, GIT 1, G protein-coupled receptor kinase-interactor 1, G protein coupled receptor kinase interactor 1, G protein coupled receptor kinase interacting ArfGAP 1, Cool-associated and tyrosine-phosphorylated protein 1, Cool associated and tyrosine phosphorylated protein 1, CAT-1, CaT1, CAT 1, ARF GTPase-activating protein GIT1, ARF GTPase activating protein GIT1, ARF GAP GIT1) Copy Product Info
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Synonyms: GRK-interacting protein 1, GRK interacting protein 1, GIT1_HUMAN, GIT 1, G protein-coupled receptor kinase-interactor 1, G protein coupled receptor kinase interactor 1, G protein coupled receptor kinase interacting ArfGAP 1, Cool-associated and tyrosine-phosphorylated protein 1, Cool associated and tyrosine phosphorylated protein 1, CAT-1, CaT1, CAT 1, ARF GTPase-activating protein GIT1, ARF GTPase activating protein GIT1, ARF GAP GIT1

Catalog No. TMAC-01662 Copy Product Info
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Anti-GIT1 Antibody (6A39) is a Rabbit antibody targeting GIT1. Anti-GIT1 Antibody (6A39) can be used in FCM,IHC,WB.
Anti-GIT1 Antibody
(6A39)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-GIT1 Antibody (6A39) is a Rabbit antibody targeting GIT1. Anti-GIT1 Antibody (6A39) can be used in FCM,IHC,WB.
SynonymsGRK-interacting protein 1, GRK interacting protein 1, GIT1_HUMAN, GIT 1, G protein-coupled receptor kinase-interactor 1, G protein coupled receptor kinase interactor 1, G protein coupled receptor kinase interacting ArfGAP 1, Cool-associated and tyrosine-phosphorylated protein 1, Cool associated and tyrosine phosphorylated protein 1, CAT-1, CaT1, CAT 1, ARF GTPase-activating protein GIT1, ARF GTPase activating protein GIT1, ARF GAP GIT1
Ig Type
IgG
Clone
6A39
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundHeterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist. G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade. GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking. GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 85 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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