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Anti-GIT1 Antibody (6A39)
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Catalog No. TMAC-01662
Alias GRK-interacting protein 1, GRK interacting protein 1, GIT1_HUMAN, GIT 1, G protein-coupled receptor kinase-interactor 1, G protein coupled receptor kinase interactor 1, G protein coupled receptor kinase interacting ArfGAP 1, Cool-associated and tyrosine-phosphorylated protein 1, Cool associated and tyrosine phosphorylated protein 1, CAT-1, CaT1, CAT 1, ARF GTPase-activating protein GIT1, ARF GTPase activating protein GIT1, ARF GAP GIT1
Anti-GIT1 Antibody (6A39) is a Rabbit antibody targeting GIT1. Anti-GIT1 Antibody (6A39) can be used in WB,IHC,FCM.
Anti-GIT1 Antibody (6A39)
Anti-GIT1 Antibody (6A39)
😃Good
Catalog No. TMAC-01662Alias GRK-interacting protein 1, GRK interacting protein 1, GIT1_HUMAN, GIT 1, G protein-coupled receptor kinase-interactor 1, G protein coupled receptor kinase interactor 1, G protein coupled receptor kinase interacting ArfGAP 1, Cool-associated and tyrosine-phosphorylated protein 1, Cool associated and tyrosine phosphorylated protein 1, CAT-1, CaT1, CAT 1, ARF GTPase-activating protein GIT1, ARF GTPase activating protein GIT1, ARF GAP GIT1
Anti-GIT1 Antibody (6A39) is a Rabbit antibody targeting GIT1. Anti-GIT1 Antibody (6A39) can be used in WB,IHC,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $296 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
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| Description | Anti-GIT1 Antibody (6A39) is a Rabbit antibody targeting GIT1. Anti-GIT1 Antibody (6A39) can be used in WB,IHC,FCM. |
| Synonyms | GRK-interacting protein 1, GRK interacting protein 1, GIT1_HUMAN, GIT 1, G protein-coupled receptor kinase-interactor 1, G protein coupled receptor kinase interactor 1, G protein coupled receptor kinase interacting ArfGAP 1, Cool-associated and tyrosine-phosphorylated protein 1, Cool associated and tyrosine phosphorylated protein 1, CAT-1, CaT1, CAT 1, ARF GTPase-activating protein GIT1, ARF GTPase activating protein GIT1, ARF GAP GIT1 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of GIT1 on A549 cell using anti-GIT1 antibody at 1/500 dilution. 2. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-GIT1 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-GIT1 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse fallopian tubes tissue using anti-GIT1 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-GIT1 antibody. Counter stained with hematoxylin. 6. Flow cytometric analysis of A549 cells with GIT1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist. G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade. GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking. GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 85 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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