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Anti-DDIT3 Antibody (2G599)
😃Good
Catalog No. TMAC-01128
Alias Growth arrest and DNA damage-inducible protein GADD153, GADD153, DNA damage-inducible transcript 3 protein, DDIT-3, DDIT3, CHOP-10, CHOP10, CHOP, CCAAT/enhancer-binding protein homologous protein, C/EBP-homologous protein 10, C/EBP-homologous protein, C/EBP zeta
Anti-DDIT3 Antibody (2G599) is a Rabbit antibody targeting DDIT3. Anti-DDIT3 Antibody (2G599) can be used in FCM,IHC,WB.
Anti-DDIT3 Antibody (2G599)
Anti-DDIT3 Antibody (2G599)
😃Good
Catalog No. TMAC-01128Alias Growth arrest and DNA damage-inducible protein GADD153, GADD153, DNA damage-inducible transcript 3 protein, DDIT-3, DDIT3, CHOP-10, CHOP10, CHOP, CCAAT/enhancer-binding protein homologous protein, C/EBP-homologous protein 10, C/EBP-homologous protein, C/EBP zeta
Anti-DDIT3 Antibody (2G599) is a Rabbit antibody targeting DDIT3. Anti-DDIT3 Antibody (2G599) can be used in FCM,IHC,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $296 | 7-10 days | 7-10 days | |
| 100 μL | $498 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-DDIT3 Antibody (2G599) is a Rabbit antibody targeting DDIT3. Anti-DDIT3 Antibody (2G599) can be used in FCM,IHC,WB. |
| Synonyms | Growth arrest and DNA damage-inducible protein GADD153, GADD153, DNA damage-inducible transcript 3 protein, DDIT-3, DDIT3, CHOP-10, CHOP10, CHOP, CCAAT/enhancer-binding protein homologous protein, C/EBP-homologous protein 10, C/EBP-homologous protein, C/EBP zeta |
| Ig Type | IgG |
| Clone | 2G599 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of DDIT3 on PC-12 cells lysates using anti-DDIT3 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-DDIT3 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human gastric carcinoma tissue using anti-DDIT3 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-DDIT3 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue using anti-DDIT3 antibody. Counter stained with hematoxylin. 6. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-DDIT3 antibody. Counter stained with hematoxylin. 7. Flow cytometric analysis of Hela cells with DDIT3 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.        |
| Application | |
| Recommended Dose | WB: 1:1000; IHC: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | GADD 153 has been described as a growth arrest and DNA damage-inducible gene that encodes a C/EBP-related nuclear protein. This protein has also been designated C/EBP-homologous protein (CHOP-10). GADD 153 expression is induced by a variety of cellular stresses, inducing nutrient deprivation and metabolic perturbations. GADD 153 functions to block cells in G1 to S phase in cell cycle progression and acts by dimerizing with other C/EBP proteins to direct GADD 153 dimers away from "classical" C/EBP binding sites, recognizing instead unique "nonclassical" sites. Thus GADD 153 acts as a negative modulator of C/EBP-like proteins in certain terminally differentiated cells, similar to the regulatory function of Id on the activity of Myo D and Myo D-related proteins involved in the development of muscle cells. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 25 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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