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Anti-ADAM10 Antibody (4B559)
(Synonyms: RAK, Mammalian disintegrin metalloprotease, MADM, Kuzbanian protein homolog, Kuzbanian, Kuz, HsT18717, HsT 18717, Drosophila, CDw156, CD156c antigen, CD156c, CD 156c, ADAM metallopeptidase domain 10, ADAM 10, AD18, AD10, AD 10, A disintegrin and metalloproteinase domain 10, A disintegrin and metalloprotease domain 10) Copy Product Info
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Synonyms: RAK, Mammalian disintegrin metalloprotease, MADM, Kuzbanian protein homolog, Kuzbanian, Kuz, HsT18717, HsT 18717, Drosophila, CDw156, CD156c antigen, CD156c, CD 156c, ADAM metallopeptidase domain 10, ADAM 10, AD18, AD10, AD 10, A disintegrin and metalloproteinase domain 10, A disintegrin and metalloprotease domain 10
Catalog No. TMAC-00085 Copy Product Info
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Anti-ADAM10 Antibody (4B559) is a Rabbit antibody targeting ADAM10. Anti-ADAM10 Antibody (4B559) can be used in IP,WB.
Anti-ADAM10 Antibody
(4B559)
(4B559)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $298 | 7-10 days | 7-10 days | |
| 100 μL | $498 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-ADAM10 Antibody (4B559) is a Rabbit antibody targeting ADAM10. Anti-ADAM10 Antibody (4B559) can be used in IP,WB. |
| Synonyms | RAK, Mammalian disintegrin metalloprotease, MADM, Kuzbanian protein homolog, Kuzbanian, Kuz, HsT18717, HsT 18717, Drosophila, CDw156, CD156c antigen, CD156c, CD 156c, ADAM metallopeptidase domain 10, ADAM 10, AD18, AD10, AD 10, A disintegrin and metalloproteinase domain 10, A disintegrin and metalloprotease domain 10 |
| Ig Type | IgG |
| Clone | 4B559 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IP: 1:10-50 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | ADAM (a disintegrin and metalloprotease) proteins are a family of over 30 membrane-anchored, glycosylated, Zn2+ dependent proteases that are involved in cell-cell, cell-matrix interface related processes including fertilization, muscle fusion, secretion of TNFα (tumor necrosis factor α), and modulation of the neurogenic function of Notch and Delta. ADAM proteins possess a signal-domain, a pro-domain, a metalloprotease domain, a disintegrin domain (integrin ligand) a cysteine-rich region, an epidermal growth factor-like domain, a transmembrane domain and a cytoplasmic tail. ADAMs are expressed in brain, testis, epididymis, ovary, breast, placenta, liver, heart, lung, bone and muscle, and catalyze proteolysis, adhesion, fusion and intracellular signaling. ADAM10 is a TNF-processing enzyme that cleaves pro-TNF, a membrane-bound precusor protein, at Ala 76-Val 77, which causes membrane shedding of soluble TNF. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 84 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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