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Anti-CXADR Monoclonal Antibody-Biotin (Synonyms: HCVADR, CVB3-binding protein, Coxsackievirus B-adenovirus rec...)
Catalog No. TMAZ-0258B Copy Product Info
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Anti-CXADR Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting CXADR. Anti-CXADR Monoclonal Antibody-Biotin can be used in ELISA,FCM.
Anti-CXADR Monoclonal Antibody-Biotin
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Catalog No. TMAZ-0258B
Synonyms HCVADR, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, Coxsackievirus and adenovirus receptor
Anti-CXADR Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting CXADR. Anti-CXADR Monoclonal Antibody-Biotin can be used in ELISA,FCM.
Anti-CXADR Monoclonal Antibody-Biotin
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μg | $196 | 12 days | 12 days | |
| 50 μg | $236 | 12 days | 12 days | |
| 100 μg | $330 | 12 days | 12 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-CXADR Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting CXADR. Anti-CXADR Monoclonal Antibody-Biotin can be used in ELISA,FCM. |
| Synonyms | HCVADR, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, Coxsackievirus and adenovirus receptor |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of CXADR overexpressed 463F cells with TMAZ-0258B, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FCM; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of CXADR protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in PBS. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair|(Microbial infection) Acts as a receptor for adenovirus type C|(Microbial infection) Acts as a receptor for Coxsackievirus B1 to B6 |
| Conjucates | Biotin |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | CXADR |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Other Functions |
| Molecular Weight | 150 kDa |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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