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Anti-CD46 Antibody (3J800)

😃Good
Catalog No. TMAC-00720

Anti-CD46 Antibody (3J800) is a Rabbit antibody targeting CD46. Anti-CD46 Antibody (3J800) can be used in WB,ICC,IHC.

Anti-CD46 Antibody (3J800)

Anti-CD46 Antibody (3J800)

😃Good
Catalog No. TMAC-00720
Anti-CD46 Antibody (3J800) is a Rabbit antibody targeting CD46. Anti-CD46 Antibody (3J800) can be used in WB,ICC,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-CD46 Antibody (3J800) is a Rabbit antibody targeting CD46. Anti-CD46 Antibody (3J800) can be used in WB,ICC,IHC.
Ig Type
IgG
Reactivity
Human,Rat
Application
Recommended Dose
WB: 1:1000-5000; IHC: 1:50-200; ICC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundCD46, also called membrane cofactor protein (MCP), is a transmembrane glycoprotein that exists as a non-disulfide-linked dimer. CD46 regulates the complement cascade by inhibiting C3b and C4b deposited on self tissue. CD46 is a cofactor that binds to C3b and C4b, allowing their degradation by a plasma serine protease called factor I. This function resides in the complement control protein repeats (CCPs), with CCP1-4 essential for regulation. CD46 is widely distributed on thymocytes, T cells, B cells, monocytes, granulocytes, NK cells, platelets, endothelial cells, epithelial cells, fibroblasts, placenta and sperm, but not on erythrocytes. It is the major high affinity receptor for measles virus and human herpes virus. Mouse cells ubiquitously express CRRY, which is a functional ortholog of human decay-accelerating factor (DAF; CD55) and membrane cofactor protein (MCP; CD46).
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 55 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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