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Anti-CD46 Antibody (3J800) (Synonyms: Trophoblast leukocyte common antigen, TLX, Membrane cofactor protein)
Catalog No. TMAC-00720 Copy Product Info
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Anti-CD46 Antibody (3J800) is a Rabbit antibody targeting CD46. Anti-CD46 Antibody (3J800) can be used in ICC,IHC,WB.
Anti-CD46 Antibody (3J800)
Copy Product Info🥰Excellent
Catalog No. TMAC-00720
Synonyms Trophoblast leukocyte common antigen, TLX, Membrane cofactor protein
Anti-CD46 Antibody (3J800) is a Rabbit antibody targeting CD46. Anti-CD46 Antibody (3J800) can be used in ICC,IHC,WB.
Anti-CD46 Antibody
(3J800)
(3J800)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $296 | 7-10 days | 7-10 days | |
| 100 μL | $497 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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| Description | Anti-CD46 Antibody (3J800) is a Rabbit antibody targeting CD46. Anti-CD46 Antibody (3J800) can be used in ICC,IHC,WB. |
| Synonyms | Trophoblast leukocyte common antigen, TLX, Membrane cofactor protein |
| Ig Type | IgG |
| Clone | 3J800 |
| Reactivity | Human,Rat |
| Verified Activity | 1. Western blot analysis of CD46 on Siha and PC-3M cell lysates using anti-CD46 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-CD46 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human breast tissue using anti-CD46 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-CD46 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-CD46 antibody. Counter stained with hematoxylin. 6. ICC staining CD46 in PC-3M cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 7. ICC staining CD46 in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.        |
| Application | |
| Recommended Dose | WB: 1:1000-5000; IHC: 1:50-200; ICC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | CD46, also called membrane cofactor protein (MCP), is a transmembrane glycoprotein that exists as a non-disulfide-linked dimer. CD46 regulates the complement cascade by inhibiting C3b and C4b deposited on self tissue. CD46 is a cofactor that binds to C3b and C4b, allowing their degradation by a plasma serine protease called factor I. This function resides in the complement control protein repeats (CCPs), with CCP1-4 essential for regulation. CD46 is widely distributed on thymocytes, T cells, B cells, monocytes, granulocytes, NK cells, platelets, endothelial cells, epithelial cells, fibroblasts, placenta and sperm, but not on erythrocytes. It is the major high affinity receptor for measles virus and human herpes virus. Mouse cells ubiquitously express CRRY, which is a functional ortholog of human decay-accelerating factor (DAF; CD55) and membrane cofactor protein (MCP; CD46). |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 55 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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