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Anti-DDB2 Antibody (1O273)
(Synonyms: UV-DDB 2, UV-damaged DNA-binding protein 2, DNA damage-binding protein 2, DDBb, DDB p48 subunit, DDB 2, Damage-specific DNA-binding protein 2) Copy Product Info
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Synonyms: UV-DDB 2, UV-damaged DNA-binding protein 2, DNA damage-binding protein 2, DDBb, DDB p48 subunit, DDB 2, Damage-specific DNA-binding protein 2
Catalog No. TMAC-01126 Copy Product Info
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Anti-DDB2 Antibody (1O273) is a Rabbit antibody targeting DDB2. Anti-DDB2 Antibody (1O273) can be used in FCM,IHC,WB.
Anti-DDB2 Antibody
(1O273)
(1O273)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $296 | 7-10 days | 7-10 days | |
| 100 μL | $497 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-DDB2 Antibody (1O273) is a Rabbit antibody targeting DDB2. Anti-DDB2 Antibody (1O273) can be used in FCM,IHC,WB. |
| Synonyms | UV-DDB 2, UV-damaged DNA-binding protein 2, DNA damage-binding protein 2, DDBb, DDB p48 subunit, DDB 2, Damage-specific DNA-binding protein 2 |
| Ig Type | IgG |
| Clone | 1O273 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Damaged DNA binding protein (DDB) is a heterodimer composed of two subunits, p127 and p48, which are designated DDB1 and DDB2, respectively. The DDB heterodimer is involved in repairing DNA damaged by ultraviolet light. Specifically, DDB, also designated UV-damaged DNA binding protein (UV-DDB), xeroderma pigmentosum group E binding factor (XPE-BF) and hepatitis B virus X-associated protein 1 (XAP-1), binds to damaged cyclobutane pyrimidine dimers (CPDs). Mutations in the DDB2 gene are implicated as causes of xeroderma pigmentosum group E, an autosomal recessive disease in which patients are defective in nucleotide excision DNA repair. XPE is characterized by hypersensitivity of the skin to sunlight with a high frequency of skin cancer as well as neurologic abnormalities. The hepatitis B virus (HBV) X protein interacts with DDB1, which may mediate HBx transactivation. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: C-terminal human DDB2 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 48 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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