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Anti-BAX Antibody (2H4)
(Synonyms: Bcl-2-like protein 4, Bcl2-L-4, BCL2L4, Apoptosis regulator BAX) Copy Product Info
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Synonyms: Bcl-2-like protein 4, Bcl2-L-4, BCL2L4, Apoptosis regulator BAX
Catalog No. TMAH-00104 Copy Product Info
🥰Excellent
Anti-BAX Antibody (2H4) is an antibody targeting BAX. Anti-BAX Antibody (2H4) can be used in ELISA,FCM,IHC.
Anti-BAX Antibody
(2H4)
(2H4)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $348 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-BAX Antibody (2H4) is an antibody targeting BAX. Anti-BAX Antibody (2H4) can be used in ELISA,FCM,IHC. |
| Synonyms | Bcl-2-like protein 4, Bcl2-L-4, BCL2L4, Apoptosis regulator BAX |
| Ig Type | Rabbit IgG |
| Clone | 2H4 |
| Reactivity | Human, Mouse |
| Application | |
| Recommended Dose | IHC:1:50-1:200; FCM:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | [Isoform Alpha]: Mitochondrion outer membrane; Single-pass membrane protein. Cytoplasm.; [Isoform Beta]: Cytoplasm.; [Isoform Gamma]: Cytoplasm.; [Isoform Delta]: Cytoplasm. |
| Tissue Specificity | Expressed in a wide variety of tissues. Isoform Psi is found in glial tumors. Isoform Alpha is expressed in spleen, breast, ovary, testis, colon and brain, and at low levels in skin and lung. Isoform Sigma is expressed in spleen, breast, ovary, testis, lu |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Plays a role in the mitochondrial apoptotic process. Under normal conditions, BAX is largely cytosolic via constant retrotranslocation from mitochondria to the cytosol mediated by BCL2L1/Bcl-xL, which avoids accumulation of toxic BAX levels at the mitochondrial outer membrane (MOM). Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human BAX |
| Antigen Species | Human |
| Gene Name | BAX |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cancer, Cell biology, Metabolism |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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