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Anti-CD71/TfR1 Antibody (Jr-141 Naked Antibody)
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Catalog No. T9901A-762
Alias JR-141 antibody (uncoupled from iduronate 2-sulfatase), Anti-human CD71/TfR1 Antibody
Anti-CD71/TfR1 Antibody (Jr-141 Naked Antibody) is a sophisticated humanized IgG1 monoclonal antibody target the human transferrin receptor 1 (TfR1/CD71) with a measured dissociation constant (Kd) of 1.12 nM, functioning as the foundational component of the J-Brain Cargo technology for research involving receptor-mediated transcytosis across the blood-brain barrier.
Anti-CD71/TfR1 Antibody (Jr-141 Naked Antibody)
Anti-CD71/TfR1 Antibody (Jr-141 Naked Antibody)
😃Good
Catalog No. T9901A-762Alias JR-141 antibody (uncoupled from iduronate 2-sulfatase), Anti-human CD71/TfR1 Antibody
Anti-CD71/TfR1 Antibody (Jr-141 Naked Antibody) is a sophisticated humanized IgG1 monoclonal antibody target the human transferrin receptor 1 (TfR1/CD71) with a measured dissociation constant (Kd) of 1.12 nM, functioning as the foundational component of the J-Brain Cargo technology for research involving receptor-mediated transcytosis across the blood-brain barrier.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | Inquiry | Inquiry | Inquiry | |
| 5 mg | Inquiry | Inquiry | Inquiry |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Anti-CD71/TfR1 Antibody (Jr-141 Naked Antibody) is a sophisticated humanized IgG1 monoclonal antibody target the human transferrin receptor 1 (TfR1/CD71) with a measured dissociation constant (Kd) of 1.12 nM, functioning as the foundational component of the J-Brain Cargo technology for research involving receptor-mediated transcytosis across the blood-brain barrier. |
| Targets&IC50 | CD71:26.4 ng/mL (EC50), Transferrin Receptor:1.12 nM (Kd) |
| In vitro | In SPR binding kinetics assays, Anti-CD71/TfR1 Antibody (Jr-141 Naked Antibody) bound to human TfR1 with a Kd of 1.12 nM and demonstrated a binding EC50 of 26.4 ng/mL [1]. |
| In vivo | In cynomolgus monkey models, systemic administration of Anti-CD71/TfR1 Antibody (Jr-141 Naked Antibody) at 2 mg/kg resulted in significant brain parenchyma accumulation [1]. |
| Synonyms | JR-141 antibody (uncoupled from iduronate 2-sulfatase), Anti-human CD71/TfR1 Antibody |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | CD71/TfR1 |
| Isotype | IgG1 |
| Storage | store at low temperature | Lyophilized powder: -20~-80°C for 1 year | Shipping with blue ice. |
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