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Anti-S100A16 Antibody (7D573)
😃Good
Catalog No. TMAY-01673
Alias S100F, S100 calcium binding protein A16, MGC17528, DT1P1A7, AAG13
Anti-S100A16 Antibody (7D573) is a Rabbit antibody targeting S100A16. Anti-S100A16 Antibody (7D573) can be used in ELISA.
Anti-S100A16 Antibody (7D573)
Anti-S100A16 Antibody (7D573)
😃Good
Catalog No. TMAY-01673Alias S100F, S100 calcium binding protein A16, MGC17528, DT1P1A7, AAG13
Anti-S100A16 Antibody (7D573) is a Rabbit antibody targeting S100A16. Anti-S100A16 Antibody (7D573) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $268 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-S100A16 Antibody (7D573) is a Rabbit antibody targeting S100A16. Anti-S100A16 Antibody (7D573) can be used in ELISA. |
| Alias | S100F, S100 calcium binding protein A16, MGC17528, DT1P1A7, AAG13 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 7D573 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human S100A16 (rh S100A16; TMPY-02135; Q96FQ6; Met1-Ser103). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | S100A16 is a member of S100 protein superfamily that carries calcium-binding EF-hand motifs. S100 proteins are cell- and tissue-specific and are involved in many intra- and extracellular processes through interacting with specific target proteins. S100A16 expression was found to be astrocyte-specific. The S100A16 protein was found to accumulate within nucleoli and to translocate to the cytoplasm in response to Ca(2+) stimulation. The homodimeric structure of human S100A16 in the apo state has been obtained both in the solid state and in solution, resulting in good agreement between the structures with the exception of two loop regions. The homodimeric solution structure of human S100A16 was also calculated in the calcium(II)-bound form. Differently from most S100 proteins, the conformational rearrangement upon calcium binding is minor. Immunoprecipitation analysis revealed that S100A16 could physically interact with tumor suppressor protein p53, also a known inhibitor of adipogenesis. Overexpression or RNA interference-initiated reduction of S100A16 led to the inhibition or activation of the expression of p53-responsive genes, respectively. S100A16 protein is a novel adipogenesis-promoting factor and that increased expression of S100A16 in 3T3-L1 adipocytes can have a negative impact on insulin sensitivity. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human S100A16 protein (TMPY-02135) |
| Antigen Species | Human |
| Biology Area | Calcium-binding Proteins and Related Molecules |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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