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Anti-ATM Antibody (9B624)
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Catalog No. TMAC-00335
Alias telomere maintenance 1, Telomere fusion protein, TELO1, TEL1, Tefu, Serine/threonine-protein kinase ATM, Serine protein kinase ATM, OTTHUMP00000232981, MGC74674, homolog, DKFZp781A0353, ATM serine/threonine kinase, ATE, ATDC, ATD, ATC, Ataxia telangiectasia mutated homolog, Ataxia telangiectasia mutated, ATA, AT1, A-T mutated homolog, A-T mutated, AT mutated
Anti-ATM Antibody (9B624) is a Rabbit antibody targeting ATM. Anti-ATM Antibody (9B624) can be used in WB,ICC/IF,IHC.
Anti-ATM Antibody (9B624)
Anti-ATM Antibody (9B624)
😃Good
Catalog No. TMAC-00335Alias telomere maintenance 1, Telomere fusion protein, TELO1, TEL1, Tefu, Serine/threonine-protein kinase ATM, Serine protein kinase ATM, OTTHUMP00000232981, MGC74674, homolog, DKFZp781A0353, ATM serine/threonine kinase, ATE, ATDC, ATD, ATC, Ataxia telangiectasia mutated homolog, Ataxia telangiectasia mutated, ATA, AT1, A-T mutated homolog, A-T mutated, AT mutated
Anti-ATM Antibody (9B624) is a Rabbit antibody targeting ATM. Anti-ATM Antibody (9B624) can be used in WB,ICC/IF,IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $296 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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| Description | Anti-ATM Antibody (9B624) is a Rabbit antibody targeting ATM. Anti-ATM Antibody (9B624) can be used in WB,ICC/IF,IHC. |
| Synonyms | telomere maintenance 1, Telomere fusion protein, TELO1, TEL1, Tefu, Serine/threonine-protein kinase ATM, Serine protein kinase ATM, OTTHUMP00000232981, MGC74674, homolog, DKFZp781A0353, ATM serine/threonine kinase, ATE, ATDC, ATD, ATC, Ataxia telangiectasia mutated homolog, Ataxia telangiectasia mutated, ATA, AT1, A-T mutated homolog, A-T mutated, AT mutated |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of ATM on CRC cell lysates using anti-ATM antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-ATM antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-ATM antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-ATM antibody. Counter stained with hematoxylin. 5. ICC staining ATM in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 6. ICC staining ATM in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 7. ICC staining ATM in CRC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| Application | |
| Recommended Dose | WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The phosphatidylinositol kinase (PIK) family members fall into two distinct subgroups. The first subgroup contains proteins such as the PI 3- and PI 4-kinases and the second group comprises the PIK-related kinases. The PIK-related kinases include Atm, DNA-PKCS and FRAP. These proteins have in common a region of homology at their carboxy-termini that is not present in the PI 3- and PI 4-kinases. The Atm gene is mutated in the autosomal recessive disorder ataxia telangiectasia (AT) that is characterized by cerebellar degeneration (ataxia) and the appearance of dilated blood vessels (telangiec-tases) in the conjunctivae of the eyes. AT cells are hypersensitive to ionizing radiation, impaired in mediating the inhibition of DNA synthesis and display delays in p53 induction. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 350 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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