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Anti-PINCH Monoclonal Antibody (2L620)
(Synonyms: PINCH-1, PINCH1, PINCH, LIMS1) Copy Product Info
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Synonyms: PINCH-1, PINCH1, PINCH, LIMS1
Catalog No. TMAC-03301 Copy Product Info
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Anti-PINCH Monoclonal Antibody (2L620) is a Mouse antibody targeting PINCH. Anti-PINCH Monoclonal Antibody (2L620) can be used in WB,IF,FCM.
Anti-PINCH Monoclonal Antibody
(2L620)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 µL | $296 | 7-10 days | 7-10 days | |
| 100 µL | $428 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-PINCH Monoclonal Antibody (2L620) is a Mouse antibody targeting PINCH. Anti-PINCH Monoclonal Antibody (2L620) can be used in WB,IF,FCM. |
| Synonyms | PINCH-1, PINCH1, PINCH, LIMS1 |
| Ig Type | IgG1 |
| Clone | 2L620 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of PINCH on different cell lysates using anti-PINCH antibody at 1/1,000 dilution. Positive control: Lane 1: A549, Lane 2: Jurkat, Lane 3: Hela. 2. ICC staining PINCH (green) and actin filaments (red) in HepG2 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. Flow cytometric analysis of Hela cells with PINCH antibody at 1/100 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red).  , , |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human PINCH expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | LIMS1 |
| Gene ID | |
| Protein Name | LIM and senescent cell antigen-like-containing domain protein 1 |
| Uniprot ID |
| Molecular Weight | Theoretical: 37 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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