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Anti-JARID2 Antibody (7C209)

(Synonyms: Protein Jumonji, Jumonji/ARID domain-containing protein 2, Jumonji/ARID domain containing protein 2, Jumonji protein, Jumonji like protein, Jumonji homolog, Jumonji AT rich interactive domain 2, JMJ, JARID2, JARID 2, JARD2_HUMAN, JARD2) Copy Product Info
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Synonyms: Protein Jumonji, Jumonji/ARID domain-containing protein 2, Jumonji/ARID domain containing protein 2, Jumonji protein, Jumonji like protein, Jumonji homolog, Jumonji AT rich interactive domain 2, JMJ, JARID2, JARID 2, JARD2_HUMAN, JARD2

Catalog No. TMAC-02279 Copy Product Info
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Anti-JARID2 Antibody (7C209) is a Mouse antibody targeting JARID2. Anti-JARID2 Antibody (7C209) can be used in FCM,ICC,WB.
Anti-JARID2 Antibody
(7C209)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4287-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-JARID2 Antibody (7C209) is a Mouse antibody targeting JARID2. Anti-JARID2 Antibody (7C209) can be used in FCM,ICC,WB.
SynonymsProtein Jumonji, Jumonji/ARID domain-containing protein 2, Jumonji/ARID domain containing protein 2, Jumonji protein, Jumonji like protein, Jumonji homolog, Jumonji AT rich interactive domain 2, JMJ, JARID2, JARID 2, JARD2_HUMAN, JARD2
Clone
7C209
Reactivity
Human
Application
Recommended Dose
WB: 1:500-2000; ICC: 1:50-200; FCM: 1:100-200
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundRegulator of histone methyltransferase complexes that plays an essential role in embryonic development, including heart and liver development, neural tube fusion process and hematopoiesis. Acts by modulating histone methyltransferase activity and promoting the recruitment of histone methyltransferase complexes to their target genes. Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells. Does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes. In embryonic stem cells, it associates with the PRC2 complex and inhibits trimethylation of 'Lys-27' of histone H3 (H3K27me3) by the PRC2 complex, thereby playing a key role in differentiation of embryonic stem cells and normal development. In cardiac cells, it is required to repress expression of cyclin-D1 (CCND1) by activating methylation of 'Lys-9' of histone H3 (H3K9me) by the GLP1/EHMT1 and G9a/EHMT2 histone methyltransferases. Also acts as a transcriptional repressor of ANF via its interaction with GATA4 and NKX2-5. Participates in the negative regulation of cell proliferation signaling.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 139 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Related Tags: Anti-JARID2 Antibody (7C209) molecular weight