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Anti-AHR Antibody (8Z303)
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Catalog No. TMAC-00277
Alias Class E basic helix-loop-helix protein 76 (bHLHe76), bHLHe76, Aryl hydrocarbon receptor, AHR, Ah receptor
Anti-AHR Antibody (8Z303) is a Rabbit antibody targeting AHR. Anti-AHR Antibody (8Z303) can be used in WB,ICC/IF.
Anti-AHR Antibody (8Z303)
Anti-AHR Antibody (8Z303)
😃Good
Catalog No. TMAC-00277Alias Class E basic helix-loop-helix protein 76 (bHLHe76), bHLHe76, Aryl hydrocarbon receptor, AHR, Ah receptor
Anti-AHR Antibody (8Z303) is a Rabbit antibody targeting AHR. Anti-AHR Antibody (8Z303) can be used in WB,ICC/IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $296 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-AHR Antibody (8Z303) is a Rabbit antibody targeting AHR. Anti-AHR Antibody (8Z303) can be used in WB,ICC/IF. |
| Synonyms | Class E basic helix-loop-helix protein 76 (bHLHe76), bHLHe76, Aryl hydrocarbon receptor, AHR, Ah receptor |
| Ig Type | IgG |
| Clone | 8Z303 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of AhR on human lung lysates using anti-AhR antibody at 1/1,000 dilution. 2. ICC staining AhR in Hela cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining AhR in MCF-7 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining AhR in NIH/3T3 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| Application | |
| Recommended Dose | WB: 1:1000-2000; ICC/IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is the prototype for a family of toxic halogenated aromatic compounds that are thought to cause adverse reproductive, immunologic and metabolic effects. Many biological responses to TCDD are mediated through ligand binding to the aromatic hydrocarbon (Ah) receptor, also known as AhR. Ah Receptor is a ligand dependent transcription factor that interacts with specific DNA sequences, termed xenobiotic responsive elements (XREs), and that lies upstream of TCDD-inducible genes. Upon binding to the ligand, Ah Receptor binds to the Ah Receptor nuclear translocator (Arnt), and the complex is translocated from the cytoplasm to the nucleus. Arnt is required for Ah R eceptor to bind to XRE. Ah Receptor and Arnt are members of a family of transcription factors that contain a basic helix-loop-helix motif and a common "PAS" motif. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 96 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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