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Anti-SF3B3 Antibody (4H951)

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Catalog No. TMAC-03718

Anti-SF3B3 Antibody (4H951) is a Rabbit antibody targeting SF3B3. Anti-SF3B3 Antibody (4H951) can be used in WB,ICC,IHC,FCM.

Anti-SF3B3 Antibody (4H951)

Anti-SF3B3 Antibody (4H951)

😃Good
Catalog No. TMAC-03718
Anti-SF3B3 Antibody (4H951) is a Rabbit antibody targeting SF3B3. Anti-SF3B3 Antibody (4H951) can be used in WB,ICC,IHC,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4967-10 days
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Product Introduction

Bioactivity
Description
Anti-SF3B3 Antibody (4H951) is a Rabbit antibody targeting SF3B3. Anti-SF3B3 Antibody (4H951) can be used in WB,ICC,IHC,FCM.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200; ICC: 1:50-100; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundSF3B is a U2 snRNP-associated protein complex essential for spliceosome assembly. SF3B contains the spliceosomal proteins SAP 49, SAP 130 (also known as SF3B3), SAP 145 and SAP 155. SF3B3, SAP 145 and SAP 155 are present in a protein complex in HeLa nuclear extracts and associate with one another. While SF3B3 and SAP 155 interact with each other (directly or indirectly) within this complex, SAP 49 and SAP 145 are known to interact directly with each other. Unexpectedly, the SAP 49-SAP 145 protein-protein interaction requires the amino-terminus of SAP 49, which contains two RNA-recognition motifs. The observation that SAP 49 and SAP 145 interact directly with both U2 snRNP and the pre-mRNA suggests that this protein complex plays a role in tethering U2 snRNP to the branch site.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: within the C-terminus of human SF3B3
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 136 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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