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Flanvotumab
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Catalog No. T77011Cas No. 1188277-05-5
Alias IMC 20D7S, 20D7S
Flanvotumab (IMC-20D7S) is a humanized monoclonal antibody targeting tyrosinase-related protein (TYRP1), exhibiting potent antitumor activity through natural killer-mediated and antibody-dependent cell-mediated cytotoxicity (ADCC).
Flanvotumab
😃Good
Catalog No. T77011Alias IMC 20D7S, 20D7SCas No. 1188277-05-5
Flanvotumab (IMC-20D7S) is a humanized monoclonal antibody targeting tyrosinase-related protein (TYRP1), exhibiting potent antitumor activity through natural killer-mediated and antibody-dependent cell-mediated cytotoxicity (ADCC).
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $157 | In Stock | In Stock | |
| 5 mg | $428 | In Stock | In Stock | |
| 10 mg | $662 | - | In Stock | |
| 25 mg | $987 | - | In Stock | |
| 50 mg | $1,370 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Flanvotumab (IMC-20D7S) is a humanized monoclonal antibody targeting tyrosinase-related protein (TYRP1), exhibiting potent antitumor activity through natural killer-mediated and antibody-dependent cell-mediated cytotoxicity (ADCC). |
| In vitro | Flanvotumab is developed based on TA99, a mouse IgG2a monoclonal antibody against TYRP1. TA99 is positioned in subcutaneous melanoma xenografts and inhibits the growth of syngeneic tumors in preclinical models[1].The antitumor effect of TA99 relies on the presence of intact antibodies, Fc receptors, and natural killer (NK) cells[1]. |
| Synonyms | IMC 20D7S, 20D7S |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | TRP1/TYRP1 |
| Molecular Weight | 145.42 kDa |
| Cas No. | 1188277-05-5 |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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