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Flanvotumab (Synonyms: IMC 20D7S, 20D7S)

Catalog No. T77011 Copy Product Info
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Flanvotumab (IMC-20D7S) is a humanized monoclonal antibody targeting tyrosinase-related protein (TYRP1), exhibiting potent antitumor activity through natural killer-mediated and antibody-dependent cell-mediated cytotoxicity (ADCC).

Flanvotumab

Copy Product Info
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Catalog No. T77011
Synonyms IMC 20D7S, 20D7S

Flanvotumab (IMC-20D7S) is a humanized monoclonal antibody targeting tyrosinase-related protein (TYRP1), exhibiting potent antitumor activity through natural killer-mediated and antibody-dependent cell-mediated cytotoxicity (ADCC).

Flanvotumab
Cas No. 1188277-05-5
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$157In StockIn Stock
5 mg$428In StockIn Stock
10 mg$662-In Stock
25 mg$987-In Stock
50 mg$1,370-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 95%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Flanvotumab (IMC-20D7S) is a humanized monoclonal antibody targeting tyrosinase-related protein (TYRP1), exhibiting potent antitumor activity through natural killer-mediated and antibody-dependent cell-mediated cytotoxicity (ADCC).
In vitro
Flanvotumab is developed based on TA99, a mouse IgG2a monoclonal antibody against TYRP1. TA99 is positioned in subcutaneous melanoma xenografts and inhibits the growth of syngeneic tumors in preclinical models[1].The antitumor effect of TA99 relies on the presence of intact antibodies, Fc receptors, and natural killer (NK) cells[1].
SynonymsIMC 20D7S, 20D7S
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetTRP1/TYRP1
Chemical Properties
Molecular Weight145.42 kDa
Cas No.1188277-05-5
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
Storage-20°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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