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Anti-OCLN Antibody (1S954) (Synonyms: Tight junction protein occludin, Occludin1, Occludin, Occludin-1, Occlu...)

Catalog No. TMAC-02912 Copy Product Info
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Anti-OCLN Antibody (1S954) is a Rabbit antibody targeting OCLN. Anti-OCLN Antibody (1S954) can be used in FCM,IP,WB.

Anti-OCLN Antibody (1S954)

Copy Product Info
🥰Excellent
Catalog No. TMAC-02912
Synonyms Tight junction protein occludin, Occludin1, Occludin, Occludin-1, Occludin, MGC34277, FLJ94056, FLJ77961, FLJ18079, FLJ08163, BLCPMG

Anti-OCLN Antibody (1S954) is a Rabbit antibody targeting OCLN. Anti-OCLN Antibody (1S954) can be used in FCM,IP,WB.

Anti-OCLN Antibody
(1S954)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-OCLN Antibody (1S954) is a Rabbit antibody targeting OCLN. Anti-OCLN Antibody (1S954) can be used in FCM,IP,WB.
SynonymsTight junction protein occludin, Occludin1, Occludin, Occludin-1, Occludin, MGC34277, FLJ94056, FLJ77961, FLJ18079, FLJ08163, BLCPMG
Ig Type
IgG
Clone
1S954
Reactivity
Human,Mouse,Rat
Verified Activity
1. Flow cytometric analysis of 293 cells with Occludin antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
2. All lanes use the Antibody at 1:1000 dilution for 1 hour at room temperature.
3. All lanes use the Antibody at 1:1000 dilution for 1 hour at room temperature.
4. All lanes use the Antibody at 1:1000 dilution for 1 hour at room temperature.
verifiedActivityverifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:1000; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundOccludin is an integral membrane protein closely associated with the tight junctions of epithelial and endothelial cells. Occludin is a tetraspan integral membrane protein in epithelial and endothelial tight junction (TJ) structures that can contain two extracellular loops. The protein exists in a variety of phosphorylated forms. Phosphorylation is involved in regulating both the localization and the function of occludin. Expression of occludin is up-regulated by poly-unsaturated fatty acids, increasing transendothelial cell resistance and reducing cellular permeability to large molecules. The level of occludin varies greatly depending on tissue; in brain tissue, occludin is highly expressed at cell-cell contact sites. Non-neural tissues show lower expression and discontinuous distribution. Up-regulation of epithelial occludin may play a role in enhancing paracellular permeability and be related to the damage to the tight junction.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 59 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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