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Anti-OCLN Antibody (1S954)
😃Good
Catalog No. TMAC-02912
Alias Tight junction protein occludin, Occludin1, Occludin, Occludin-1, Occludin, MGC34277, FLJ94056, FLJ77961, FLJ18079, FLJ08163, BLCPMG
Anti-OCLN Antibody (1S954) is a Rabbit antibody targeting OCLN. Anti-OCLN Antibody (1S954) can be used in FCM,IP,WB.
Anti-OCLN Antibody (1S954)
Anti-OCLN Antibody (1S954)
😃Good
Catalog No. TMAC-02912Alias Tight junction protein occludin, Occludin1, Occludin, Occludin-1, Occludin, MGC34277, FLJ94056, FLJ77961, FLJ18079, FLJ08163, BLCPMG
Anti-OCLN Antibody (1S954) is a Rabbit antibody targeting OCLN. Anti-OCLN Antibody (1S954) can be used in FCM,IP,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $497 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-OCLN Antibody (1S954) is a Rabbit antibody targeting OCLN. Anti-OCLN Antibody (1S954) can be used in FCM,IP,WB. |
| Synonyms | Tight junction protein occludin, Occludin1, Occludin, Occludin-1, Occludin, MGC34277, FLJ94056, FLJ77961, FLJ18079, FLJ08163, BLCPMG |
| Ig Type | IgG |
| Clone | 1S954 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Flow cytometric analysis of 293 cells with Occludin antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. 2. All lanes use the Antibody at 1:1000 dilution for 1 hour at room temperature. 3. All lanes use the Antibody at 1:1000 dilution for 1 hour at room temperature. 4. All lanes use the Antibody at 1:1000 dilution for 1 hour at room temperature.     |
| Application | |
| Recommended Dose | WB: 1:1000; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Occludin is an integral membrane protein closely associated with the tight junctions of epithelial and endothelial cells. Occludin is a tetraspan integral membrane protein in epithelial and endothelial tight junction (TJ) structures that can contain two extracellular loops. The protein exists in a variety of phosphorylated forms. Phosphorylation is involved in regulating both the localization and the function of occludin. Expression of occludin is up-regulated by poly-unsaturated fatty acids, increasing transendothelial cell resistance and reducing cellular permeability to large molecules. The level of occludin varies greatly depending on tissue; in brain tissue, occludin is highly expressed at cell-cell contact sites. Non-neural tissues show lower expression and discontinuous distribution. Up-regulation of epithelial occludin may play a role in enhancing paracellular permeability and be related to the damage to the tight junction. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 59 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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