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Synonyms: RNC_HUMAN, RNASEN, RNaseIII, RNASE3L, RNase3, RNase III, RNase 3, RN3, RN 3, RibonucleaseIII, Ribonuclease type III nuclear, Ribonuclease III nuclear, Ribonuclease III, Ribonuclease 3, RANSE3L, Putative ribonuclease III, Putative protein p241 which interacts with transcription factor Sp1, Protein Drosha, p241, Nuclear RNase III Drosha, HSA242976, Etohi2, Drosha ribonuclease type III, Drosha double stranded RNA specific endoribonuclease, DROSHA
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $496 | 7-10 days | 7-10 days |
| Description | Anti-Drosha Antibody (5J107) is a Rabbit antibody targeting Drosha. Anti-Drosha Antibody (5J107) can be used in FCM,ICC,IF,IHC,WB. |
| Synonyms | RNC_HUMAN, RNASEN, RNaseIII, RNASE3L, RNase3, RNase III, RNase 3, RN3, RN 3, RibonucleaseIII, Ribonuclease type III nuclear, Ribonuclease III nuclear, Ribonuclease III, Ribonuclease 3, RANSE3L, Putative ribonuclease III, Putative protein p241 which interacts with transcription factor Sp1, Protein Drosha, p241, Nuclear RNase III Drosha, HSA242976, Etohi2, Drosha ribonuclease type III, Drosha double stranded RNA specific endoribonuclease, DROSHA |
| Ig Type | IgG |
| Clone | 5J107 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The ribonuclease III superfamily represents a structurally distinct group of double-strand-specific endonucleases with essential roles in RNA maturation, RNA decay, and gene silencing. Initial cleavage of microRNAs is catalysed by Drosha, a nuclease of the RNase III family, which acts on primary miRNA transcripts (pri-miRNAs) in the nucleus. Human Drosha is a component of two multi-protein complexes. The larger complex contains multiple classes of RNA-associated proteins including RNA helicases, proteins that bind double-stranded RNA, novel heterogeneous nuclear ribonucleoproteins and the Ewing's sarcoma family of proteins. The smaller complex is composed of Drosha and the double-stranded-RNA-binding protein, DGCR8. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 159 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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