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Anti-SUN2 Antibody (2Y616)
😃Good
Catalog No. TMAC-03917
Alias UNC84B, unc84, C. elegans, homolog of, B, unc84 homolog B (C. elegans), unc84 homolog B, UNC 84B, SUN domain-containing protein 2, SUN 2, Sad1/unc-84 protein-like 2, Sad1/unc84 protein-like, Sad1 unc-84 domain protein 2, Sad1 unc84 domain protein, Sad1 and UNC84 domain containing 2, RAB5IP, Rab5 interacting protein, Protein unc-84 homolog B, nuclear envelope protein, KIAA0668, FRIGG
Anti-SUN2 Antibody (2Y616) is a Rabbit antibody targeting SUN2. Anti-SUN2 Antibody (2Y616) can be used in WB,IHC,FCM,ICC,IF.
Anti-SUN2 Antibody (2Y616)
Anti-SUN2 Antibody (2Y616)
😃Good
Catalog No. TMAC-03917Alias UNC84B, unc84, C. elegans, homolog of, B, unc84 homolog B (C. elegans), unc84 homolog B, UNC 84B, SUN domain-containing protein 2, SUN 2, Sad1/unc-84 protein-like 2, Sad1/unc84 protein-like, Sad1 unc-84 domain protein 2, Sad1 unc84 domain protein, Sad1 and UNC84 domain containing 2, RAB5IP, Rab5 interacting protein, Protein unc-84 homolog B, nuclear envelope protein, KIAA0668, FRIGG
Anti-SUN2 Antibody (2Y616) is a Rabbit antibody targeting SUN2. Anti-SUN2 Antibody (2Y616) can be used in WB,IHC,FCM,ICC,IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
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Chemical Properties
| Description | Anti-SUN2 Antibody (2Y616) is a Rabbit antibody targeting SUN2. Anti-SUN2 Antibody (2Y616) can be used in WB,IHC,FCM,ICC,IF. |
| Synonyms | UNC84B, unc84, C. elegans, homolog of, B, unc84 homolog B (C. elegans), unc84 homolog B, UNC 84B, SUN domain-containing protein 2, SUN 2, Sad1/unc-84 protein-like 2, Sad1/unc84 protein-like, Sad1 unc-84 domain protein 2, Sad1 unc84 domain protein, Sad1 and UNC84 domain containing 2, RAB5IP, Rab5 interacting protein, Protein unc-84 homolog B, nuclear envelope protein, KIAA0668, FRIGG |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of SUN2 on rat kidney tissue lysate using anti-SUN2 antibody at 1/2,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded rat epididymis tissue using anti-SUN2 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-SUN2 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-SUN2 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue using anti-SUN2 antibody. Counter stained with hematoxylin. 6. Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-SUN2 antibody. Counter stained with hematoxylin. 7. ICC staining SUN2 (green) in SK-Br-3 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 8. Flow cytometric analysis of SK-Br-3 cells with SUN2 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody. |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:50-200; ICC:IF: 1:50-100; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | SUN2 (sad1/unc-84 protein-like 2), also known as UNC84B (unc-84 homolog B), FRIGG, KIAA0668 or RAB5IP, is a 717 amino acid single-pass membrane protein that contains one SUN domain and localizes to the membrane of both the nucleus and the endosome. Widely expressed in a variety of tissues, including lung, muscle and heart, SUN2 interacts with Rab 5A and may play a role in homotypic endosome fusion. The gene encoding SUN2 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias. |
| Conjucates | Unconjugated |
| Uniprot ID |
| Molecular Weight | Theoretical: 80 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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