Shopping Cart
Remove All
Your shopping cart is currently empty
Enoblituzumab
(Synonyms: TJ-271, MGA271) Copy Product Info
🥰Excellent
Synonyms: TJ-271, MGA271
Catalog No. T9901A-002 Copy Product Info
Purity: 95%
🥰Excellent
Enoblituzumab is a humanized IgG1 κmab monoclonal antibody that recognizes human B7-H3 protein and can be used to study solid tumors such as non-small cell lung cancer (NSCLC).
Cas No. 1353485-38-7
Customer service consultation
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $195 | - | In Stock | |
| 5 mg | $483 | - | In Stock | |
| 10 mg | $692 | - | In Stock | |
| 25 mg | $1,080 | - | In Stock | |
| 50 mg | $1,490 | - | In Stock | |
| 100 mg | $2,100 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
Batch Information
Select Batch
Purity:96.7% (SDS-PAGE); 98.5% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Enoblituzumab is a humanized IgG1 κmab monoclonal antibody that recognizes human B7-H3 protein and can be used to study solid tumors such as non-small cell lung cancer (NSCLC). |
| In vitro | Enoblituzumab interacts with B7-H3, resulting in potent antibody-dependent cellular cytotoxicity (ADCC) across a broad range of cancer cells[2]. It effectively mediates ADCC against A498 cells at concentrations ranging from 0.01 ng/mL to 10 mg/mL using cynomolgus monkey peripheral blood mononuclear cells (PBMCs)[3]. |
| In vivo | In mice (mCD16-/-hCD16A+) with murine CD16 gene knocked out and transgenic for human CD16A-158F, enoblituzumab (5 mg/kg; i.v.; single dose) exhibits an estimated half-life of 249 hours with a Cmax of 43 mg/mL[3]. Exhibiting potent antitumor activity in xenograft mice models of renal cell and bladder carcinoma expressing B7-H3, enoblituzumab (0.1-10 mg/kg; i.v.; once weekly; 5 weeks) shows this effect[3]. |
| Endotoxin | <1.0 EU/mg |
| Synonyms | TJ-271, MGA271 |
| Reactivity | Human |
| Verified Activity | Immobilized Human B7-H3 Protein (His) (TMPY-02031) at 1 μg/mL (100 μL/well) can bind Enoblituzumab. The EC50 is 2.90 ng/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | B7-H3/CD276 |
| Molecular Weight | 145.81 kDa |
| Cas No. | 1353485-38-7 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Calculator
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: Enoblituzumab chemical structure | Enoblituzumab in vivo | Enoblituzumab in vitro | Enoblituzumab molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.