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Anti-DYNLL1 Antibody (5G489) (Synonyms: Protein Inhibitor of Neuronal Nitric Oxide Synthase, PIN, HDLC1, DYNL...)
Catalog No. TMAC-01200 Copy Product Info
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Anti-DYNLL1 Antibody (5G489) is a Rabbit antibody targeting DYNLL1. Anti-DYNLL1 Antibody (5G489) can be used in ICC/IF,IHC,IP,WB.
Anti-DYNLL1 Antibody (5G489)
Copy Product Info🥰Excellent
Catalog No. TMAC-01200
Synonyms Protein Inhibitor of Neuronal Nitric Oxide Synthase, PIN, HDLC1, DYNLL1, Dynein Light Chain LC8-Type 1, Dynein Light Chain 1 Cytoplasmic, DNCLC1, DNCL1, DLC8, DLC1, 8 kDa Dynein Light Chain
Anti-DYNLL1 Antibody (5G489) is a Rabbit antibody targeting DYNLL1. Anti-DYNLL1 Antibody (5G489) can be used in ICC/IF,IHC,IP,WB.
Anti-DYNLL1 Antibody
(5G489)
(5G489)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $296 | 7-10 days | 7-10 days | |
| 100 μL | $496 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-DYNLL1 Antibody (5G489) is a Rabbit antibody targeting DYNLL1. Anti-DYNLL1 Antibody (5G489) can be used in ICC/IF,IHC,IP,WB. |
| Synonyms | Protein Inhibitor of Neuronal Nitric Oxide Synthase, PIN, HDLC1, DYNLL1, Dynein Light Chain LC8-Type 1, Dynein Light Chain 1 Cytoplasmic, DNCLC1, DNCL1, DLC8, DLC1, 8 kDa Dynein Light Chain |
| Ig Type | IgG |
| Clone | 5G489 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of DYNLL1 on MCF-7 cells lysates using anti-DYNLL1 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-DYNLL1 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded rat esophagus tissue using anti-DYNLL1 antibody. Counter stained with hematoxylin. 4. ICC staining DYNLL1 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. ICC staining DYNLL1 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 6. ICC staining DYNLL1 in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.       |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Dyneins are multisubunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein heavy, intermediate, light and light-intermediate chains are all components of minus end-directed motors; the complex transports cellular cargos towards the central region of the cell. The highly conserved DYNLL proteins were originally identified as light chains for microtubule-based motor protein Dynein. In mammals there are two closely related isoforms expressed, DYNLL1 and DYNLL2 which share 93% sequence identity at the protein level. DYNLL1 (Dynein light chain 1) also designated, DLC8 or PIN (Protein inhibitor of neuronal nitric oxide synthase) has been identified as a protein that interacts with NOS1 resulting in NOS1 inhibition. Dimerization is required for NOS1 activity and DYNLL1 has been shown to destabilize the NOS1 dimer. Nitric oxide may be involved in several processes such as apoptosis, synaptogenesis and neuronal development; thus DYNLL1 is implicated in these processes as well. DYNLL1 is a ubiquitously expressed protein that exhibits high expression in testis and moderate expression in brain. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 10 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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