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Anti-C17ORF53 Antibody (1Z939)

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Catalog No. TMAC-00502

Anti-C17ORF53 Antibody (1Z939) is a Mouse antibody targeting C17ORF53. Anti-C17ORF53 Antibody (1Z939) can be used in WB,ICC,FCM.

Anti-C17ORF53 Antibody (1Z939)

Anti-C17ORF53 Antibody (1Z939)

😃Good
Catalog No. TMAC-00502
Anti-C17ORF53 Antibody (1Z939) is a Mouse antibody targeting C17ORF53. Anti-C17ORF53 Antibody (1Z939) can be used in WB,ICC,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4287-10 days
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Product Introduction

Bioactivity
Description
Anti-C17ORF53 Antibody (1Z939) is a Mouse antibody targeting C17ORF53. Anti-C17ORF53 Antibody (1Z939) can be used in WB,ICC,FCM.
Reactivity
Human
Application
Recommended Dose
WB: 1:500-1000; ICC: 1:50-200; FCM: 1:100-200
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
Research BackgroundC17orf53 (chromosome 17 open reading frame 53) is a 647 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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