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Anti-C17ORF53 Antibody (1Z939)
😃Good
Catalog No. TMAC-00502
Alias Uncharacterized protein C17orf53, MGC3130, Hypothetical protein LOC78995, FLJ11594, CQ053_HUMAN, Chromosome 17 open reading frame 53, C17orf53
Anti-C17ORF53 Antibody (1Z939) is a Mouse antibody targeting C17ORF53. Anti-C17ORF53 Antibody (1Z939) can be used in FCM,ICC,WB.
Anti-C17ORF53 Antibody (1Z939)
Anti-C17ORF53 Antibody (1Z939)
😃Good
Catalog No. TMAC-00502Alias Uncharacterized protein C17orf53, MGC3130, Hypothetical protein LOC78995, FLJ11594, CQ053_HUMAN, Chromosome 17 open reading frame 53, C17orf53
Anti-C17ORF53 Antibody (1Z939) is a Mouse antibody targeting C17ORF53. Anti-C17ORF53 Antibody (1Z939) can be used in FCM,ICC,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $428 | 7-10 days |
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| Description | Anti-C17ORF53 Antibody (1Z939) is a Mouse antibody targeting C17ORF53. Anti-C17ORF53 Antibody (1Z939) can be used in FCM,ICC,WB. |
| Synonyms | Uncharacterized protein C17orf53, MGC3130, Hypothetical protein LOC78995, FLJ11594, CQ053_HUMAN, Chromosome 17 open reading frame 53, C17orf53 |
| Clone | 1Z939 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of C17ORF53 on human C17ORF53 recombinant protein using anti-C17ORF53 antibody at 1/1,000 dilution. 2. Western blot analysis of C17ORF53 on HEK293 (1) and C17ORF53-hIgGFc transfected HEK293 (2) cell lysate using anti-C17ORF53 antibody at 1/1,000 dilution. 3. ICC staining C17ORF53 (green) in HepG2 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. Flow cytometric analysis of Jurkat cells with C17ORF53 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red). |
| Application | |
| Recommended Dose | WB: 1:500-1000; ICC: 1:50-200; FCM: 1:100-200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
| Research Background | C17orf53 (chromosome 17 open reading frame 53) is a 647 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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