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Anti-AURKB Antibody (8W890) (Synonyms: STK5, STK12, STK-1, STK1, Serine/threonine-protein kinase aurora-B, ...)

Catalog No. TMAC-00351 Copy Product Info
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Anti-AURKB Antibody (8W890) is a Rabbit antibody targeting AURKB. Anti-AURKB Antibody (8W890) can be used in ICC/IF,IHC,IP,WB.

Anti-AURKB Antibody (8W890)

Copy Product Info
🥰Excellent
Catalog No. TMAC-00351
Synonyms STK5, STK12, STK-1, STK1, Serine/threonine-protein kinase aurora-B, Serine/threonine-protein kinase 5, Serine/threonine-protein kinase 12, EC 2.7.11.1, Aurora-related kinase 2, Aurora/IPL1-related kinase 2, Aurora kinase B, Aurora- and IPL1-like midbody-associated protein 1, Aurora 1, ARK-2, ARK2, AIRK2, AIM-1, AIM1, AIK2

Anti-AURKB Antibody (8W890) is a Rabbit antibody targeting AURKB. Anti-AURKB Antibody (8W890) can be used in ICC/IF,IHC,IP,WB.

Anti-AURKB Antibody
(8W890)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-AURKB Antibody (8W890) is a Rabbit antibody targeting AURKB. Anti-AURKB Antibody (8W890) can be used in ICC/IF,IHC,IP,WB.
SynonymsSTK5, STK12, STK-1, STK1, Serine/threonine-protein kinase aurora-B, Serine/threonine-protein kinase 5, Serine/threonine-protein kinase 12, EC 2.7.11.1, Aurora-related kinase 2, Aurora/IPL1-related kinase 2, Aurora kinase B, Aurora- and IPL1-like midbody-associated protein 1, Aurora 1, ARK-2, ARK2, AIRK2, AIM-1, AIM1, AIK2
Ig Type
IgG
Clone
8W890
Reactivity
Human
Verified Activity
1. Western blot analysis of Aurora B on different lysates using anti-Aurora B antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: MCF-7.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Aurora B antibody. Counter stained with hematoxylin.
verifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundAurora related kinase-1 (ARK-1, STK15, Aurora2, Aik1) and -2 (ARK-2, STK12, Aurora1) are centrosome-associated serine/ threonine kinases that regulate centrosome separation, bipolar spindle assembly, and chromosome segregation during mitosis. ARK-1 and -2 are expressed in the nucleus and localize to distinct portions of mitotic machinery such as the centrosome, spindle poles (ARK-1), and midbody (ARK-2) during mitosis. ARK-1 and -2 transcripts are present at high levels in human thymus and fetal liver. ARK-1 protein has elevated expression in colon carcinoma lines (HT-29, SNU-C2B, COLO 205, SW480, 837 and 948) and accumulates during metaphase in HeLa cells. ARK-2 protein levels are maximal during both S and G2/M phases, whereas ARK-1 protein is degraded after G2/M via the ubiquitin-proteasome pathway. ARK-2 has a unique genetic loci relative to ARK-1, suggesting that these two kinases, with oncogenic potential, have different roles in cell cycle progression.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 39 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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