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Myostatin inhibitory peptide 2

Name: Myostatin inhibitory peptide 2
Brand: TargetMol
SKU: TP2528
Rating: 4.5 (1 reviews)

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Catalog No. TP2528 Copy Product Info

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Myostatin inhibitory peptide 2 is a 24-amino-acid peptide derived from amino acids 20-43 of the mouse myostatin prodomain, and serves as a potent myostatin inhibitor. Myostatin inhibitory peptide 2 binds directly to myostatin with high affinity (Kd=35.9 nM), blocks the binding of myostatin to ActRII receptor, and inhibits the activation of downstream Smad2 signaling pathway. In mdx mice, a model of muscular dystrophy, Myostatin inhibitory peptide 2 significantly increases skeletal muscle weight and is suitable for research on mechanisms and interventions of muscular atrophy diseases.

Cas No. 1621169-52-5

Pack Size	Price	USA Stock	Global Stock	Quantity
10 mg	Inquiry	Inquiry	Inquiry
50 mg	Inquiry	Inquiry	Inquiry

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.

For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	2956.49
Formula	C₁₃₃H₂₂₇N₄₃O₃₃
Cas No.	1621169-52-5
Smiles	C([C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(N)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)CCCCN)=O)CO)=O)CC(C)C)=O)[C@H](CC)C)=O)CCC(N)=O)=O)[C@H](CC)C)=O)CCCCN)=O)[C@H](CC)C)=O)C)=O)CCC(O)=O)=O)[C@H](CC)C)=O)CCCNC(=N)N)=O)CO)=O)=O)CCCNC(=N)N)=O)[C@@H](C)O)=O)CC(N)=O)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)NC([C@H](C)N)=O)C=2C=3C(NC2)=CC=CC3
Sequence	Ala-Trp-Arg-Gln-Asn-Thr-Arg-Tyr-Ser-Arg-Ile-Glu-Ala-Ile-Lys-Ile-Gln-Ile-Leu-Ser-Lys-Leu-Arg-Leu-NH₂
Sequence Short	AWRQNTRYSRIEAIKIQILSKLRL

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Keywords

Myostatin inhibitory peptide-2

Related Tags: Myostatin inhibitory peptide 2 chemical structure | Myostatin inhibitory peptide 2 formula | Myostatin inhibitory peptide 2 molecular weight