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ACE-031

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Catalog No. TP2528Cas No. 1621169-52-5
Alias Myostatin inhibitory peptide 7

ACE-031 (Myostatin inhibitory peptide 7) is a recombinant protein that fuses the Fc region of human immunoglobulin IgG1 with the type IIB activin receptor (ActRIIB). This compound inhibits myostatin and other factors that negatively regulate muscle growth, thereby promoting muscle growth.

ACE-031

ACE-031

😃Good
Catalog No. TP2528Alias Myostatin inhibitory peptide 7Cas No. 1621169-52-5
ACE-031 (Myostatin inhibitory peptide 7) is a recombinant protein that fuses the Fc region of human immunoglobulin IgG1 with the type IIB activin receptor (ActRIIB). This compound inhibits myostatin and other factors that negatively regulate muscle growth, thereby promoting muscle growth.
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Product Introduction

Bioactivity
Description
ACE-031 (Myostatin inhibitory peptide 7) is a recombinant protein that fuses the Fc region of human immunoglobulin IgG1 with the type IIB activin receptor (ActRIIB). This compound inhibits myostatin and other factors that negatively regulate muscle growth, thereby promoting muscle growth.
SynonymsMyostatin inhibitory peptide 7
Chemical Properties
Molecular Weight2956.49
FormulaC133H227N43O33
Cas No.1621169-52-5
SmilesC([C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(N)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)CCCCN)=O)CO)=O)CC(C)C)=O)[C@H](CC)C)=O)CCC(N)=O)=O)[C@H](CC)C)=O)CCCCN)=O)[C@H](CC)C)=O)C)=O)CCC(O)=O)=O)[C@H](CC)C)=O)CCCNC(=N)N)=O)CO)=O)=O)CCCNC(=N)N)=O)[C@@H](C)O)=O)CC(N)=O)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)NC([C@H](C)N)=O)C=2C=3C(NC2)=CC=CC3
SequenceAla-Trp-Arg-Gln-Asn-Thr-Arg-Tyr-Ser-Arg-Ile-Glu-Ala-Ile-Lys-Ile-Gln-Ile-Leu-Ser-Lys-Leu-Arg-Leu-NH2
Sequence ShortAWRQNTRYSRIEAIKIQILSKLRL
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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