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Anti-BAK1 Antibody (2V22)
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Catalog No. TMAC-00372
Alias CDN1, Bcl-2-like protein 7, Bcl2-L-7, BCL2L7, Bcl-2 homologous antagonist/killer, BAK 1, BAK, Apoptosis regulator BAK
Anti-BAK1 Antibody (2V22) is a Rabbit antibody targeting BAK1. Anti-BAK1 Antibody (2V22) can be used in WB,ICC/IF,IHC,IP,FCM.
Anti-BAK1 Antibody (2V22)
Anti-BAK1 Antibody (2V22)
😃Good
Catalog No. TMAC-00372Alias CDN1, Bcl-2-like protein 7, Bcl2-L-7, BCL2L7, Bcl-2 homologous antagonist/killer, BAK 1, BAK, Apoptosis regulator BAK
Anti-BAK1 Antibody (2V22) is a Rabbit antibody targeting BAK1. Anti-BAK1 Antibody (2V22) can be used in WB,ICC/IF,IHC,IP,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $496 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-BAK1 Antibody (2V22) is a Rabbit antibody targeting BAK1. Anti-BAK1 Antibody (2V22) can be used in WB,ICC/IF,IHC,IP,FCM. |
| Synonyms | CDN1, Bcl-2-like protein 7, Bcl2-L-7, BCL2L7, Bcl-2 homologous antagonist/killer, BAK 1, BAK, Apoptosis regulator BAK |
| Ig Type | IgG |
| Clone | 2V22 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of Bak on different lysates using anti-Bak antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: Human skeletal muscle, Lane 3: Ags. 2. Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-Bak antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti-Bak antibody. Counter stained with hematoxylin. 4. ICC staining Bak in CRC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. Flow cytometric analysis of NIH/3T3 cells with Bak antibody at 1/50 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The Bcl-2 family of proteins is characterized by its ability to modulate cell death (apoptosis) under a broad range of physiologic conditions. Bcl-2 and several related proteins function to inhibit apoptosis, while other members of the Bcl-2 family, such as Bax, accelerate death under various conditions. One member of the Bcl-2 family, designated Bak, functions primarily to enhance apoptotic cell death following appropriate activating signals and counteracts the protection from apoptosis provided by Bcl-2. Expression of Bak is widespread in a broad range of cells, including various long-lived, terminally differentiated cell types, suggesting that its cell-death-inducing activity is broadly distributed and that the regulation of inhibitors of apoptosis may represent an important determinant of tissue-specific modulation of apoptosis. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 23 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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