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Anti-Nudel Antibody (5F982)

😃Good
Catalog No. TMAC-02900
Alias Protein Nudel, NUDEL, NudE nuclear distribution gene E homolog like 1 A. nidulans, NudE nuclear distribution gene E homolog like 1, NUDE like protein, Nuclear distribution protein nudE-like 1, Nuclear distribution protein nudE like 1, Nuclear distribution gene E like homolog 1, NDEL1_HUMAN, NDEL1, Ndel 1, Mitosin-associated protein 1, Mitosin associated protein MITAP1, Mitosin associated protein 1, MITAP1, MITAP 1, EOPA, ENDOOLIGOPEPTIDASE A, DKFZp451M0318, A. nidulans

Anti-Nudel Antibody (5F982) is a Rabbit antibody targeting Nudel. Anti-Nudel Antibody (5F982) can be used in WB,IHC.

Anti-Nudel Antibody (5F982)

Anti-Nudel Antibody (5F982)

😃Good
Catalog No. TMAC-02900Alias Protein Nudel, NUDEL, NudE nuclear distribution gene E homolog like 1 A. nidulans, NudE nuclear distribution gene E homolog like 1, NUDE like protein, Nuclear distribution protein nudE-like 1, Nuclear distribution protein nudE like 1, Nuclear distribution gene E like homolog 1, NDEL1_HUMAN, NDEL1, Ndel 1, Mitosin-associated protein 1, Mitosin associated protein MITAP1, Mitosin associated protein 1, MITAP1, MITAP 1, EOPA, ENDOOLIGOPEPTIDASE A, DKFZp451M0318, A. nidulans
Anti-Nudel Antibody (5F982) is a Rabbit antibody targeting Nudel. Anti-Nudel Antibody (5F982) can be used in WB,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4967-10 days
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Product Introduction

Bioactivity
Description
Anti-Nudel Antibody (5F982) is a Rabbit antibody targeting Nudel. Anti-Nudel Antibody (5F982) can be used in WB,IHC.
SynonymsProtein Nudel, NUDEL, NudE nuclear distribution gene E homolog like 1 A. nidulans, NudE nuclear distribution gene E homolog like 1, NUDE like protein, Nuclear distribution protein nudE-like 1, Nuclear distribution protein nudE like 1, Nuclear distribution gene E like homolog 1, NDEL1_HUMAN, NDEL1, Ndel 1, Mitosin-associated protein 1, Mitosin associated protein MITAP1, Mitosin associated protein 1, MITAP1, MITAP 1, EOPA, ENDOOLIGOPEPTIDASE A, DKFZp451M0318, A. nidulans
Ig Type
IgG
Clone
5F982
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of Nudel on rat brain tissue lysate using anti-Nudel antibody at 1/2,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-Nudel antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human small intestine tissue using anti-Nudel antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-Nudel antibody. Counter stained with hematoxylin.
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundNudE-like protein (Ndel1) is expressed in the testis, brain, heart, hypothalamus, liver, lung, spleen, and stomach, specifically in the interphase centrosome and mitotic spindle. It positively regulates minus-end directed dynein. Evidence suggests that Ndel1 interacts with LIS1 to sustain the function of dynein, thereby impacting microtubule organization, nuclear translocation, and neuronal positioning. Ndel1 is phosphorylated during mitosis and seems to tether dynactin and dynein to the mother centriole for microtubule anchoring. Loss of function of Ndel1 in the developing neocortex impairs neuronal positioning and uncouples the centrosome and nucleus. Ndel1 may also impair mitochondrial transport or function, initiating a cascade of events culminating in psychiatric illness such as lissencephaly and schizophrenia.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 38 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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