Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-TCF7L2 Antibody (8D555) (Synonyms: Transcription factor 7-like 2, Transcription factor 7 like 2 T cell spe...)

Catalog No. TMAC-03995 Copy Product Info
🥰Excellent
Anti-TCF7L2 Antibody (8D555) is a Rabbit antibody targeting TCF7L2. Anti-TCF7L2 Antibody (8D555) can be used in FCM,ICC/IF,IHC,IP,WB.

Anti-TCF7L2 Antibody (8D555)

Copy Product Info
🥰Excellent
Catalog No. TMAC-03995
Synonyms Transcription factor 7-like 2, Transcription factor 7 like 2 T cell specific HMG box, Transcription factor 7 like 2, TF7L2_HUMAN, TCF7L2 protein, TCF7L2, TCF-4, TCF4, TCF 4, T-cell-specific transcription factor 4, T-cell factor 4, T cell specific transcription factor 4, T cell specific HMG box, T cell factor 4, hTCF-4, hTCF 4, HMG box transcription factor 4

Anti-TCF7L2 Antibody (8D555) is a Rabbit antibody targeting TCF7L2. Anti-TCF7L2 Antibody (8D555) can be used in FCM,ICC/IF,IHC,IP,WB.

Anti-TCF7L2 Antibody
(8D555)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2987-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Questions
TargetMol
View More

Product Introduction

Bioactivity
Description
Anti-TCF7L2 Antibody (8D555) is a Rabbit antibody targeting TCF7L2. Anti-TCF7L2 Antibody (8D555) can be used in FCM,ICC/IF,IHC,IP,WB.
SynonymsTranscription factor 7-like 2, Transcription factor 7 like 2 T cell specific HMG box, Transcription factor 7 like 2, TF7L2_HUMAN, TCF7L2 protein, TCF7L2, TCF-4, TCF4, TCF 4, T-cell-specific transcription factor 4, T-cell factor 4, T cell specific transcription factor 4, T cell specific HMG box, T cell factor 4, hTCF-4, hTCF 4, HMG box transcription factor 4
Ig Type
IgG
Clone
8D555
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of TCF7L2 on Jurkat cells lysates using anti-TCF7L2 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-TCF7L2 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-TCF7L2 antibody. Counter stained with hematoxylin.
4. ICC staining TCF7L2 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. ICC staining TCF7L2 in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. ICC staining TCF7L2 in D3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
7. Flow cytometric analysis of Jurkat cells with TCF7L2 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
verifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundT cell factors (TCFs) comprise a family of DNA-binding transcriptional activators that are essential for lymphoid cell development. These transcription factors are activated by the Wnt-1 and Wingless pathways and are characterized by the presence of a conserved protein motif, the high mobility group (HMG) 1 box, which mediates DNA binding. TCF-4 mainly localizes in the cytoplasm and is transported into the nucleus directly bound to β-catenin in a cooperative manner. This TCF-4/β-catenin complex induces expression of Wnt target genes, including multiple cancer-associated genes. c-Jun also interacts with TCF-4 and β-catenin, and the phosphorylation-dependent interaction between c-Jun and TCF4 regulates intestinal tumorigenesis by integrating JNK and APC/β-catenin. TCF-4 is also implicated in bipolar affective disorder.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 68 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Dilution Calculator
  • Reconstitution Calculator
Related Tags: buy Anti-TCF7L2 Antibody (8D555) | purchase Anti-TCF7L2 Antibody (8D555) | Anti-TCF7L2 Antibody (8D555) cost | order Anti-TCF7L2 Antibody (8D555) | Anti-TCF7L2 Antibody (8D555) molecular weight