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Anti-AXIN2 Antibody (6U272) is a Rabbit antibody targeting AXIN2. Anti-AXIN2 Antibody (6U272) can be used in ICC/IF,IHC,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $498 | 7-10 days | 7-10 days |
| Description | Anti-AXIN2 Antibody (6U272) is a Rabbit antibody targeting AXIN2. Anti-AXIN2 Antibody (6U272) can be used in ICC/IF,IHC,WB. |
| Ig Type | IgG |
| Clone | 6U272 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:10-50; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | b-catenin is a component of both the cadherin cell adhesion system and the Wnt signaling pathway. Wnt signaling increases the amount of b-catenin, by preventing its ubiquitination and degradation, allowing its direct interaction with transcription factors of the lymphoid enhancer factor-T cell factor family and modulation of gene expression. Axin is involved in the degradation of b-catenin by acting as a scaffold to form a complex between b-catenin, adenomatous polyposis coli (APC) and GSK-3b. APC, which is phosphorylated by GSK-3b, induces degradation of b-catenin, thus inhibiting Wnt signal transduction. Conductin is 45% identical to axin and appears to play a similar role to axin in the Wnt signaling pathway. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 94 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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