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Anti-CBX2 Antibody (6H584)

😃Good
Catalog No. TMAH-00148
Alias Chromobox protein homolog 2, CBX 2

Anti-CBX2 Antibody (6H584) is an antibody targeting CBX2. Anti-CBX2 Antibody (6H584) can be used in ELISA, WB.

Anti-CBX2 Antibody (6H584)

Anti-CBX2 Antibody (6H584)

😃Good
Catalog No. TMAH-00148Alias Chromobox protein homolog 2, CBX 2
Anti-CBX2 Antibody (6H584) is an antibody targeting CBX2. Anti-CBX2 Antibody (6H584) can be used in ELISA, WB.
Pack SizePriceAvailabilityQuantity
50 μL$209 7-10 days
100 μL$347 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Recombinant Rabbit Monoclonal

Application: ELISA, WB

Reactivity: Human, Rat
AliasChromobox protein homolog 2, CBX 2
Ig Type
Rabbit IgG
Clone
6H584
Reactivity
Human, Rat
Verified Activity
Western Blot
-Positive WB detected in: U251 whole cell lysate, Ntera-2 whole cell lysate, Hela whole cell lysate, MCF-7 whole cell lysate, HepG2 whole cell lysate, HEK293 whole cell lysate, Rat heart tissue
-All lanes: CBX2 antibody at 1:2000
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 57, 24 kDa
-Observed band size: 60-72 kDa
Application
ELISA, WB
Recommended Dose
WB:1:500-1:2000.
Antibody Type
Monoclonal
Subcellular LocalizationNucleus. Chromosome.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundComponent of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Binds to histone H3 trimethylated at 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3). Plays a role in the lineage differentiation of the germ layers in embryonic development. Involved in sexual development, acting as activator of NR5A1 expression.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human CBX2
Antigen Species
Human
Gene ID
84733
Uniprot ID
Biology Area
Epigenetics and Nuclear Signaling
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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