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Anti-CBX2 Antibody (6H584) is an antibody targeting CBX2. Anti-CBX2 Antibody (6H584) can be used in ELISA,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $347 | 7-10 days | 7-10 days |
| Description | Anti-CBX2 Antibody (6H584) is an antibody targeting CBX2. Anti-CBX2 Antibody (6H584) can be used in ELISA,WB. |
| Synonyms | Chromobox protein homolog 2, CBX 2 |
| Ig Type | Rabbit IgG |
| Clone | 6H584 |
| Reactivity | Human, Rat |
| Verified Activity | Western Blot -Positive WB detected in: U251 whole cell lysate, Ntera-2 whole cell lysate, Hela whole cell lysate, MCF-7 whole cell lysate, HepG2 whole cell lysate, HEK293 whole cell lysate, Rat heart tissue -All lanes: CBX2 antibody at 1:2000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 57, 24 kDa -Observed band size: 60-72 kDa |
| Application | |
| Recommended Dose | WB:1:500-1:2000. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Nucleus. Chromosome. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Binds to histone H3 trimethylated at 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3). Plays a role in the lineage differentiation of the germ layers in embryonic development. Involved in sexual development, acting as activator of NR5A1 expression. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human CBX2 |
| Antigen Species | Human |
| Gene Name | CBX2 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Epigenetics and Nuclear Signaling |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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