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Anti-CBX2 Antibody (6H584) is an antibody targeting CBX2. Anti-CBX2 Antibody (6H584) can be used in ELISA, WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $209 | 7-10 days | |
100 μL | $347 | 7-10 days |
Description | Antibody Type: Recombinant Rabbit Monoclonal Application: ELISA, WB Reactivity: Human, Rat |
Alias | Chromobox protein homolog 2, CBX 2 |
Ig Type | Rabbit IgG |
Clone | 6H584 |
Reactivity | Human, Rat |
Verified Activity | Western Blot -Positive WB detected in: U251 whole cell lysate, Ntera-2 whole cell lysate, Hela whole cell lysate, MCF-7 whole cell lysate, HepG2 whole cell lysate, HEK293 whole cell lysate, Rat heart tissue -All lanes: CBX2 antibody at 1:2000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 57, 24 kDa -Observed band size: 60-72 kDa |
Application | ELISA, WB |
Recommended Dose | WB:1:500-1:2000. |
Antibody Type | Monoclonal |
Subcellular Localization | Nucleus. Chromosome. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Research Background | Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Binds to histone H3 trimethylated at 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3). Plays a role in the lineage differentiation of the germ layers in embryonic development. Involved in sexual development, acting as activator of NR5A1 expression. |
Conjucates | Unconjugated |
Immunogen | A synthetic peptide: Human CBX2 |
Antigen Species | Human |
Gene ID | 84733 |
Uniprot ID | |
Biology Area | Epigenetics and Nuclear Signaling |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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