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Anti-XRCC1 Antibody (5W492)

😃Good
Catalog No. TMAC-04300

Anti-XRCC1 Antibody (5W492) is a Rabbit antibody targeting XRCC1. Anti-XRCC1 Antibody (5W492) can be used in WB,IHC.

Anti-XRCC1 Antibody (5W492)

Anti-XRCC1 Antibody (5W492)

😃Good
Catalog No. TMAC-04300
Anti-XRCC1 Antibody (5W492) is a Rabbit antibody targeting XRCC1. Anti-XRCC1 Antibody (5W492) can be used in WB,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4987-10 days
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Product Introduction

Bioactivity
Description
Anti-XRCC1 Antibody (5W492) is a Rabbit antibody targeting XRCC1. Anti-XRCC1 Antibody (5W492) can be used in WB,IHC.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe x-ray repair cross-complementing (XRCC) proteins are responsible for efficiently repairing and maintaining genetic stability following DNA base damage. These genes share sequence similarity with the yeast DNA repair protein Rad5. XRCC1 is a protein that facilitates the DNA base excision repair pathway by interacting with DNA ligase III and DNA polymerase to repair DNA single-strand breaks. XRCC2 and XRCC3 are both involved in maintaining chromosome stability during cell division. XRCC2 is required for efficient repair of DNA double-strand breaks by homologous recombination between sister chromatids, and XRCC3 interacts directly with Rad51 to cooperate with Rad51 during recombinational repair. XRCC4 is an accessory factor of DNA ligase IV that preferentially binds DNA with nicks or broken ends. XRCC4 binds to DNA ligase IV and enhances its joining activity, and it is also involved in V(D)J recombination. Any defect in one of the known components of the DNA repair/V(D)J recombination machinery (Ku-70, Ku-80, DNA-PKCS, XRCC4 and DNA ligase IV) leads to abortion of the V(D)J rearrangement process and early block in both T and B cell maturation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 100/70 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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