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Anti-FLRT2 Antibody (5I699)
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Catalog No. TMAY-01833
Alias FLRT2, fibronectin leucine rich transmembrane protein 2
Anti-FLRT2 Antibody (5I699) is a Mouse antibody targeting FLRT2. Anti-FLRT2 Antibody (5I699) can be used in ELISA.
Anti-FLRT2 Antibody (5I699)
Anti-FLRT2 Antibody (5I699)
😃Good
Catalog No. TMAY-01833Alias FLRT2, fibronectin leucine rich transmembrane protein 2
Anti-FLRT2 Antibody (5I699) is a Mouse antibody targeting FLRT2. Anti-FLRT2 Antibody (5I699) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-FLRT2 Antibody (5I699) is a Mouse antibody targeting FLRT2. Anti-FLRT2 Antibody (5I699) can be used in ELISA. |
| Alias | FLRT2, fibronectin leucine rich transmembrane protein 2 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 5I699 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human FLRT2 (rh FLRT2; TMPY-02048; O43155; Met 1-Ser 539). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Fibronectin Leucine-Rich Transmembrane (FLRT) proteins are glycosylated membrane proteins expressed at the cell surface which localise in a homophilic manner to cell-cell contacts expressing the focal adhesion marker vinculin. FLRT1, FLRT2, and FLRT3, the three genes encode putative type I transmembrane proteins, each containing 10 leucine-rich repeats (LRR), a type III fibronectin (FN) domain, followed by the transmembrane region, and a short cytoplasmic tail. FLRT family members may function in cell adhesion and/or receptor signalling. Each member of the FLRT family has a distinct, highly regulated expression pattern, as was seen for the NLRR family. FLRT2 is expressed in a subset of the sclerotome, adjacent to the region that forms the syndetome, suggesting that interaction with FGF signalling may be a general property of FLRT proteins. All FLRTs can interact with FGFR1 and FLRTs can be induced by the activation of FGF signalling by FGF-2. FLRT proteins have a dual role, promoting FGF signalling and modulating homotypic cell adhesion. FLRT2 played critical roles in craniofacial development, and it was also present in the vomero-nasal organ, mandibular primodia, and the posterior aspects of the unfused and fused secondary palatal shelves. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human FLRT2 protein (TMPY-02048) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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