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Anti-RARA Antibody (6U643) (Synonyms: Retinoic acid receptor alpha polypeptide, Retinoic acid receptor alpha, ...)

Catalog No. TMAC-03584 Copy Product Info
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Anti-RARA Antibody (6U643) is a Rabbit antibody targeting RARA. Anti-RARA Antibody (6U643) can be used in FCM,WB.

Anti-RARA Antibody (6U643)

Copy Product Info
🥰Excellent
Catalog No. TMAC-03584
Synonyms Retinoic acid receptor alpha polypeptide, Retinoic acid receptor alpha, Retinoic acid nuclear receptor alpha variant 2, Retinoic acid nuclear receptor alpha variant 1, RARalpha1, RARalpha, RAR alpha, RAR, Nucleophosmin retinoic acid receptor alpha fusion protein NPM RAR long form, Nuclear receptor subfamily 1 group B member 1, Nuclear mitotic apparatus protein retinoic acid receptor alpha fusion protein, NR1B1

Anti-RARA Antibody (6U643) is a Rabbit antibody targeting RARA. Anti-RARA Antibody (6U643) can be used in FCM,WB.

Anti-RARA Antibody
(6U643)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-RARA Antibody (6U643) is a Rabbit antibody targeting RARA. Anti-RARA Antibody (6U643) can be used in FCM,WB.
SynonymsRetinoic acid receptor alpha polypeptide, Retinoic acid receptor alpha, Retinoic acid nuclear receptor alpha variant 2, Retinoic acid nuclear receptor alpha variant 1, RARalpha1, RARalpha, RAR alpha, RAR, Nucleophosmin retinoic acid receptor alpha fusion protein NPM RAR long form, Nuclear receptor subfamily 1 group B member 1, Nuclear mitotic apparatus protein retinoic acid receptor alpha fusion protein, NR1B1
Ig Type
IgG
Clone
6U643
Reactivity
Human,Mouse
Application
Recommended Dose
WB: 1:1000; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundRetinoids (RA) are metabolites of vitamin A (retinol) that are important signaling molecules during vertebrate development and tissue differentiation. RAs activate the retinoic acid receptor (RAR) and retinoid X receptor (RXR) nuclear transcription factor families. Most retinoid forms activate RAR family members, whereas RXR family members are activated by 9-cis-RA only. RAR family members, which include RARα, RARβ and RARγ, have a high affinity for all transretinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. RAR isoforms are expressed in distinct patterns throughout development and in the mature organism. The human RARα gene maps to chromosome 17 and is implicated in the chromosomal translocation associated with acute promyelocytic leukemia (APL-M3). Specifically, the RARα gene is fused with the promyelocytic leukemia (PML) gene, which encodes the fusion protein PML/RARα. The PML/RARα fusion protein inhibits PML-dependent apoptotic pathways and halts myeloid differentiation at the promyelocytic stage.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 55 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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