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DL-3-Indolylglycine

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Catalog No. T19258Cas No. 6747-15-5
Alias α-Amino-1H-indole-3-acetic acid, D,L-3-Indolylglycine

D, L-3-indolylglycine is an unnatural amino acid very similar to tryptophan, and its indole portion is directly connected to the α-position. Target: D, L-3-indolyl glycine can be used for functional protein design. One study described the inclusion of similar aza-indolylglycine moieties in peptidomimetics in order to functionally replace tryptophan moieties.

DL-3-Indolylglycine

DL-3-Indolylglycine

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Catalog No. T19258Alias α-Amino-1H-indole-3-acetic acid, D,L-3-IndolylglycineCas No. 6747-15-5
D, L-3-indolylglycine is an unnatural amino acid very similar to tryptophan, and its indole portion is directly connected to the α-position. Target: D, L-3-indolyl glycine can be used for functional protein design. One study described the inclusion of similar aza-indolylglycine moieties in peptidomimetics in order to functionally replace tryptophan moieties.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$307-10 days7-10 days
10 mg$477-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
D, L-3-indolylglycine is an unnatural amino acid very similar to tryptophan, and its indole portion is directly connected to the α-position. Target: D, L-3-indolyl glycine can be used for functional protein design. One study described the inclusion of similar aza-indolylglycine moieties in peptidomimetics in order to functionally replace tryptophan moieties.
Synonymsα-Amino-1H-indole-3-acetic acid, D,L-3-Indolylglycine
Chemical Properties
Molecular Weight190.1986
FormulaC10H10N2O2
Cas No.6747-15-5
SmilesNC(C(O)=O)c1c[nH]c2ccccc12
Relative Density.1.422g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 10.67 mg/mL (56.1 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM5.2577 mL26.2883 mL52.5766 mL262.8831 mL
5 mM1.0515 mL5.2577 mL10.5153 mL52.5766 mL
10 mM0.5258 mL2.6288 mL5.2577 mL26.2883 mL
20 mM0.2629 mL1.3144 mL2.6288 mL13.1442 mL
50 mM0.1052 mL0.5258 mL1.0515 mL5.2577 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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