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Anti-Cbl-c Antibody (6C478) is a Mouse antibody targeting Cbl-c. Anti-Cbl-c Antibody (6C478) can be used in ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μL | $199 | 7-10 days | 7-10 days |
| Description | Anti-Cbl-c Antibody (6C478) is a Mouse antibody targeting Cbl-c. Anti-Cbl-c Antibody (6C478) can be used in ELISA. |
| Synonyms | RNF57, CBL-SL, CBL-3, Cbl proto-oncogene C, E3 ubiquitin protein ligase |
| Ig Type | Mouse IgG2b |
| Clone | 6C478 |
| Reactivity | Human |
| Specificity | Human Cbl-c |
| Application | |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Cbl-c / CBL-3 (rh Cbl-c / CBL-3; TMPY-03510; AAH28915.1; Met1-Ala474). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | CBL proteins, such as Cbl-c, are phosphorylated upon activation of a variety of receptors that signal via protein tyrosine kinases. Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling. Cbl-c is a member of the Cbl family of E3 ubiquitin ligases. Expression of Cbl-c gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for Cbl-c gene. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human Cbl-c / CBL-3 Protein (TMPY-03510) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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